Somatostatin | CAS No. 51110-01-1

Somatostatin

Basic Information

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CAS Number

51110-01-1

Molecular Formula

C76H104N18O19S2

Molecular Weight

1637.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

H2O: 1 mg/mL

SMILES

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CC(C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)C(C)N)C(=O)O)CO)C(C)O)CC6=CC=CC=C6)O

InChI

InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)

InChIKey

NHXLMOGPVYXJNR-UHFFFAOYSA-N

LogP

-4.91360000000001

Topological Polar Surface Area

613.2299999999999 Å²

Hydrogen Bond Donor/Acceptor

26 / 37

Complexity

3240

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

38916-34-6
L000577
SOMATOSTATIN
BCA11001
FT-0630640
Stilamin
NCGC00181005-01
Somiaton
51110-01-1
AGCKNFFWKTFTSC (modifications: Disulfide bridge between 3 - 14)
AY 24910
Panhibin
AGCKNFFWKTFTSC
Somatotropin release-inhibiting factor
HB3088
Aminopan
19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-37-[[2-(2-aminopropanoylamino)acetyl]amino]-13,25,28-tribenzyl-10,16-bis(1-hydroxyethyl)-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
SCHEMBL3046327
Somatostatin-14
EINECS 256-969-7
SRIF 14
CCRIS 7071
Somatostatin 14
Somatostain Acetate
SRIF
AKOS015896026
NHXLMOGPVYXJNR-UHFFFAOYSA-N
somatostatin
somatostatin gamma-irradiated*cell culture tested
H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bond)
Somatostatin Acetate

MDL Number

MFCD00076762

FAQ

What is Somatostatin (CAS: 51110-01-1)?

Somatostatin is a nine-amino acid peptide hormone with the chemical formula C53H79N17O17S2. It plays a crucial role in inhibiting the release of several hormones, including growth hormone, insulin, and glucagon. Somatostatin is also known for its anti-inflammatory and neuroprotective properties.

What are the main uses of Somatostatin (CAS: 51110-01-1)?

Somatostatin is primarily used in the treatment of acromegaly, Cushing's disease, and other hormone-related disorders. It is also effective in managing symptoms of carcinoid syndrome, managing hyperglycemia in type 1 diabetes, and reducing the frequency of pancreatitis attacks. Additionally, it is used in research for studying hormone secretion and as an imaging agent in certain diagnostic procedures.

Is Somatostatin (CAS: 51110-01-1) safe?

Somatostatin is generally considered safe when used under medical supervision. However, it can cause side effects such as headache, nausea, and diarrhea. It is essential to follow the prescribed dosage and consult a healthcare provider for any concerns. Patients with a history of certain conditions, such as adrenal insufficiency or hypothyroidism, should be monitored closely.

How should Somatostatin (CAS: 51110-01-1) be stored?

Somatostatin should be stored refrigerated at 2-8°C (36-46°F) to maintain its potency. It should be protected from light and kept in its original container or a suitable, light-resistant container. Avoid freezing to prevent degradation of the peptide. Store away from heat and direct sunlight to ensure the stability of the compound.