6-Methoxy-2-naphthol

Basic Information

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CAS Number

5111-66-0

Molecular Formula

C11H10O2

Molecular Weight

174.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Physical State

Solid

Melting Point

148-152 °C

Boiling Point

336.7±15.0 °C at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

211.8±5.3 °C

Refractive Index

1.64

SMILES

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COC1=CC2=C(C=C1)C=C(C=C2)O

InChI

InChI=1S/C11H10O2/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h2-7,12H,1H3

InChIKey

WWPKRXOOVICNJY-UHFFFAOYSA-N

LogP

2.5540000000000003

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

170

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DTXSID70199117
6-Methoxynaphthalen-2-ol (Hydroxynerolin)
6-METHOXY-.BETA.-NAPHTHOL
6-methoxynaphthalen-2-ol
BDBM36292
6-Methoxy-2-naphthol, analytical standard
A828446
Q27276458
UNII-DL375UDR3E
EN300-203817
6-Methoxynaphthalen-2-ol; Naproxen Imp. H (EP); Hydroxynerolin; Naproxen Impurity H
DIETHANOLAMINEHYDROCHLORIDE
6-methoxy-naphthalen-2-ol
2-Hydroxy-6-methoxynaphthalene
NSC 149908
Naproxen impurity H [EP]
DL375UDR3E
SCHEMBL547847
6-methoxynaphthalen-2-ol;6-METHOXY-2-NAPHTHOL
6-Methoxy-naphthalene-2-ol
AKOS007930807
NAPROXEN SODIUM IMPURITY H [EP IMPURITY]
6-Methoxy-2-naphthol
SY102105
MFCD00088677
6-methoxynaphthalene-2-ol
6-Methoxy-2-naphthol, >=97.0% (HPLC)
W-202924
6-Methoxy-2-naphthol, pharmaceutical impurity standard
2-Naphthalenol, 6-methoxy-
FT-0635543

MDL Number

MFCD00088677

Customs Code

2909500000

FAQ

What regulatory guidelines apply to 6-Methoxy-2-naphthol (CAS: 5111-66-0)?

6-Methoxy-2-naphthol (CAS: 5111-66-0) falls under the purview of several regulations. In Europe, it is covered by the REACH regulation, which requires manufacturers and importers to register substances with the European Chemicals Agency. Globally, the GHS system classifies it as a flammable liquid. In the United States, it is regulated by the EPA for environmental protection and by the FDA for any potential use in pharmaceuticals. Proper documentation and safety data sheets (SDS) are essential for handling and storage.

Are there alternatives to 6-Methoxy-2-naphthol (CAS: 5111-66-0) in synthesis?

Alternatives to 6-Methoxy-2-naphthol (CAS: 5111-66-0) in synthesis include similar compounds such as 2-naphthol and its other methoxy derivatives. In some applications, 1-naphthol can serve as a substitute. Additionally, chemists might consider using naphthalene derivatives that differ in functional groups or structure to achieve similar or better outcomes. The choice depends on the specific requirements of the synthesis process and the desired properties of the final product.

What is the market or research trend for 6-Methoxy-2-naphthol (CAS: 5111-66-0)?

The market for 6-Methoxy-2-naphthol (CAS: 5111-66-0) is driven by its use in the pharmaceutical, cosmetics, and dye industries. Research trends indicate an increasing focus on the compound's application in drug intermediates and as a precursor for other naphthol derivatives. Recent studies also explore its potential in analytical chemistry and environmental science applications. The growing demand for personalized medicine is likely to boost its market, while advances in green chemistry may also influence its use in more sustainable processes.

How should waste containing 6-Methoxy-2-naphthol (CAS: 5111-66-0) be handled?

Waste containing 6-Methoxy-2-naphthol (CAS: 5111-66-0) should be collected in appropriate, labeled containers and stored in a cool, well-ventilated area away from heat sources and incompatible materials. Before disposal, ensure that the waste is neutralized and treated to minimize environmental impact. Incineration is a common method for waste disposal, but professional waste disposal services are recommended to ensure compliance with local regulations. Always follow safety protocols and environmental protection measures to avoid contamination and ensure worker safety.