2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]in deno[1,2-d][1,3]dioxol]-6b'-yl]-2-oxoethyl acetate

Basic Information

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CAS Number

51022-69-6

Molecular Formula

C28H35FO7

Molecular Weight

502.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Boiling Point

635.9°C (rough estimate)

Refractive Index

1.5860 (estimate)

SMILES

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CC(=O)OCC(=O)[C@]12OC3(CCCC3)O[C@@H]2C[C@H]4[C@@H]5CCC6=CC(=O)C=C[C@]6(C)[C@@]5(F)[C@@H](O)C[C@@]41C

InChI

InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1

InChIKey

ILKJAFIWWBXGDU-MOGDOJJUSA-N

LogP

3.5238000000000023

Topological Polar Surface Area

99.13000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 7

Synonyms & References

English

Amcinonide
CL-34699
Amciderm
Amcinonid
Amcinopol
Amicla
cyclocort
Penticort
Visderm
CL 34699
(11alpha,16alpha)-21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-pregna-1,4-diene-3,20-dione

MDL Number

MFCD00213379

FAQ

What regulatory guidelines apply to 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]inden-2',6'-dioxol]-6b'-yl]-2-oxoethyl acetate (CAS: 51022-69-6)?

This compound (CAS: 51022-69-6) should comply with GHS classification for handling and storage, as well as REACH regulations for its production and import. FDA and EPA regulations may also apply due to its use in pharmaceuticals or environmental applications. Specific labeling and documentation requirements must be followed to ensure safety and compliance.

Are there alternatives to 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]inden-2',6'-dioxol]-6b'-yl]-2-oxoethyl acetate (CAS: 51022-69-6) in synthesis?

There are several alternatives, including isomers and analogs such as 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10b',10a',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]inden-2',6'-dioxol]-6b'-yl]-2-oxoethyl acetate (CAS: 51022-70-7) and 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]inden-2',6'-dioxol]-6b'-yl]-2-oxoethyl acetate (CAS: 51022-71-8). Common alternatives include the use of different functional groups or substitution patterns.

What is the market or research trend for 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]inden-2',6'-dioxol]-6b'-yl]-2-oxoethyl acetate (CAS: 51022-69-6)?

The market trend for this compound is growing due to its potential applications in pharmaceuticals and materials science. Research is focusing on its use as a precursor in the synthesis of complex organic molecules and its potential biological activity. Price trends are influenced by supply chain dynamics and demand from the pharmaceutical industry.

How should waste containing 2-[(4a'S,4b'R,5'S,6a'S,6b'S,9a'R,10a'S,10b'S)-4b'-Fluoro-5'-hydroxy-4a',6a'-dimethyl-2'-oxo-2',4a',4b',5',6',6a',9a',10',10a',10b',11',12'-dodecahydro-6b'H-spiro[cyclopentane-1,8'-naphtho[2',1':4,5]inden-2',6'-dioxol]-6b'-yl]-2-oxoethyl acetate (CAS: 51022-69-6) be handled?

Waste containing this compound should be collected in compatible containers and stored under appropriate conditions to prevent contamination or reaction. Proper incineration or professional waste disposal services should be utilized to ensure safe and environmentally responsible disposal. Adhere to local environmental protection laws and guidelines to manage and dispose of waste effectively.