Ambroxol EP Impurity E (Bromhexine EP Impurity B)

Basic Information

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CAS Number

50910-55-9

Molecular Formula

C7H5Br2NO

Molecular Weight

278.93 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Yellow powder

Melting Point

130-135 °C

Boiling Point

319.9℃/760mmHg

Refractive Index

1.6400 (estimate)

SMILES

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C1=C(C=C(C(=C1C=O)N)Br)Br

InChI

InChI=1S/C7H5Br2NO/c8-5-1-4(3-11)7(10)6(9)2-5/h1-3H,10H2

InChIKey

RCPAZWISSAVDEA-UHFFFAOYSA-N

LogP

2.6063

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

153

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

AS-12042
EC 256-841-0
EN300-136846
RCPAZWISSAVDEA-UHFFFAOYSA-N
BROMHEXINE IMPURITY B
InChI=1/C7H5Br2NO/c8-5-1-4(3-11)7(10)6(9)2-5/h1-3H,10H
MFCD00671100
3,5-DIBROMO-2-AMINOBENZALDEHYDE
W-105925
HY-107849
FT-0611038
2-Amino-3,5-dibromobenzaldehyde, 97%
Benzaldehyde, 2-amino-3,5-dibromo-
CS-0030731
SY038949
NS00001499
AMY16465
SCHEMBL285148
AC-31356
F12175
A828361
BCP06911
EINECS 256-841-0
2-Amino-3,5-dibromobenzaldehyde
2-amino-3,5-dibromo-benzaldehyde
Z1269136164
DTXSID70198943
AC-10733
AKOS015854696
BP-12420
50910-55-9

MDL Number

MFCD00671100

Customs Code

2922399090

FAQ

What is Ambroxol EP Impurity E (CAS: 50910-55-9)?

Ambroxol EP Impurity E, also known as Bromhexine EP Impurity B, is a chemical compound identified by the CAS number 50910-55-9. It is an impurity commonly found in pharmaceutical preparations of ambroxol, a mucolytic agent used to treat respiratory conditions. This compound is typically a white to off-white crystalline solid with a molecular formula of C12H17BrO3 and a molecular weight of 289.18 g/mol. It exhibits solubility in ethanol and is often analyzed for quality control in drug manufacturing.

What are the main uses of Ambroxol EP Impurity E (CAS: 50910-55-9)?

Ambroxol EP Impurity E (CAS: 50910-55-9) is primarily used in the pharmaceutical industry as an analytical reference for quality control of ambroxol-based medications. It may also be used in research settings to study impurity profiles and ensure the purity of drug substances. Additionally, it serves as a component in the synthesis of other compounds and is relevant in drug development and regulatory testing processes.

Is Ambroxol EP Impurity E (CAS: 50910-55-9) safe?

Ambroxol EP Impurity E (CAS: 50910-55-9) is generally considered safe when handled according to standard laboratory protocols. However, as with any chemical, it should be treated with caution, especially during handling and storage. Safety measures include using appropriate personal protective equipment (PPE) and following good chemical hygiene practices. It is important to consult safety data sheets (SDS) for detailed toxicity information and handling guidelines.

How should Ambroxol EP Impurity E (CAS: 50910-55-9) be stored?

Ambroxol EP Impurity E (CAS: 50910-55-9) should be stored in a cool, dry, and well-ventilated place, away from direct light. It is typically kept in a sealed container to maintain its stability and prevent contamination. Proper storage conditions include maintaining a temperature below 25°C and humidity levels below 60%. Storage should also comply with regulatory standards for chemical handling and safety.