1-Benzyl-4-piperidinamine

Basic Information

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CAS Number

50541-93-0

Molecular Formula

C12H18N2

Molecular Weight

190.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Yellow to Brown Liquid

Boiling Point

152 ºC (9.7 mmHg)

Solubility

10g/l

Refractive Index

n20/D 1.543(lit.)

SMILES

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C1CN(CCC1N)CC2=CC=CC=C2

InChI

InChI=1S/C12H18N2/c13-12-6-8-14(9-7-12)10-11-4-2-1-3-5-11/h1-5,12H,6-10,13H2

InChIKey

YUBDLZGUSSWQSS-UHFFFAOYSA-N

LogP

1.6096999999999995

Topological Polar Surface Area

29.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

156

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Air Sensitive

Synonyms & References

English

phenylmethyl 4-aminopiperidine
n-benzyl-4-aminopiperidine
1-Benzyl-4-piperidylamine
AC-2456
NSC730607
4-amino-1-benzyl piperidine
SDCCGMLS-0066225.P001
NSC 730607
1-benzyl-piperidin-4-ylamin
1-benzyl-4-piperidineamine
phenylmethyl-4-piperidinamine
SR-01000597197-1
N-Benzyl-4-amino piperidine
BB 0241889
50541-93-0
AB00776
4-Amino-1-benzylpiperidine, 98%
1-phenylmethyl-4-piperidinamine
Z104477026
EINECS 256-620-9
Oprea1_198193
1-(Phenylmethyl)4-piperidinamine
J-513823
AM20060363
1-benzyl-piperidin-4-yl-amine
4-amino-1-(phenylmethyl)piperidine
A1086
1-benzylpiperidin-4-ylamine
1-benzyl 4-amino piperidine
A7492
2-AMINO-1-BENZYLPIPERIDINE

MDL Number

MFCD00006504

Customs Code

29333999

FAQ

What are the physical and chemical properties of 1-Benzyl-4-piperidinamine (CAS: 50541-93-0)?

1-Benzyl-4-piperidinamine is a colorless or light yellow crystalline solid. Its molecular weight is approximately 215.31 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is less reactive compared to other primary amines and does not readily undergo electrophilic substitution reactions.

How is 1-Benzyl-4-piperidinamine (CAS: 50541-93-0) typically synthesized?

1-Benzyl-4-piperidinamine can be synthesized via the reaction of piperidine with benzyl bromide in the presence of a base, such as potassium carbonate. The process yields a primary amine with high selectivity and moderate to good yield, depending on the reaction conditions.

What industries use 1-Benzyl-4-piperidinamine (CAS: 50541-93-0)?

1-Benzyl-4-piperidinamine is primarily used in the pharmaceutical industry as a precursor for the synthesis of various piperidinyl benzyl derivatives. It also finds applications in sensor technology and as a stabilizer in polymer formulations.

What precautions should be taken when handling 1-Benzyl-4-piperidinamine (CAS: 50541-93-0)?

When handling 1-Benzyl-4-piperidinamine, ensure the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a well-ventilated area and use a fume hood during operations. In case of spills, neutralize with an acid-base buffer and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.