2-Methylpyrimidine

Basic Information

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CAS Number

5053-43-0

Molecular Formula

C5H6N2

Molecular Weight

94.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

-4°C

Boiling Point

165.6°C (rough estimate)

Refractive Index

n20/D 1.4930

SMILES

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CC1=NC=CC=N1

InChI

InChI=1S/C5H6N2/c1-5-6-3-2-4-7-5/h2-4H,1H3

InChIKey

LNJMHEJAYSYZKK-UHFFFAOYSA-N

LogP

0.7850199999999998

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Methylpyrimidine
2-Me-pyrimidine
2-methyl-1,3-diazine
2-Methyl-pyrimidin
2-methyl-pyrimidine
2-methylpyrimidine(2-methyl-pyrimidine)
Pyrimidine,2-methyl
Pyrimidine,2-methyl-(6CI,7CI,8CI,9CI)
Pyrimidine, 2-methyl-
2-Methyl PYRIMIDINE
LNJMHEJAYSYZKK-UHFFFAOYSA-N
PubChem21974
PYR131
AM1034
FCH1122130
TRA0014574
HP21231
L311
HC210259
TL8003355
AB0014640
AX8077354
A828158
053M430
2-Methyl-1,3-diazine
2-methylpyrimidine

MDL Number

MFCD00128182

FAQ

What regulatory guidelines apply to 2-Methylpyrimidine (CAS: 5053-43-0)?

2-Methylpyrimidine (CAS: 5053-43-0) falls under the scope of REACH regulations in the European Union, which require manufacturers and importers to register substances above a certain tonnage threshold. It is also subject to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which mandates specific hazard communication requirements such as safety data sheets (SDS) and labels. In the United States, the Environmental Protection Agency (EPA) may regulate its use under the Toxic Substances Control Act (TSCA).

Are there alternatives to 2-Methylpyrimidine (CAS: 5053-43-0) in synthesis?

Several alternatives to 2-Methylpyrimidine (CAS: 5053-43-0) exist in synthesis, including 2-Aminopyrimidine and 2-Hydroxypyrimidine. These compounds offer similar structural features but may differ in reactivity and handling. Alternative reagents like pyridine derivatives or other pyrimidine analogs can often be used as substitutes in synthetic processes.

What is the market or research trend for 2-Methylpyrimidine (CAS: 5053-43-0)?

The market for 2-Methylpyrimidine (CAS: 5053-43-0) shows steady growth due to its applications in pharmaceuticals, particularly as a precursor in the synthesis of certain antiviral drugs. Research trends are focusing on developing more efficient and environmentally friendly synthesis methods. Additionally, there is increasing interest in exploring its potential in agrochemicals and biocatalysis.

How should waste containing 2-Methylpyrimidine (CAS: 5053-43-0) be handled?

Waste containing 2-Methylpyrimidine (CAS: 5053-43-0) should be collected in appropriate containers and stored in a well-ventilated area away from ignition sources. For incineration, it is recommended to follow strict safety protocols to ensure complete combustion and minimize environmental impact. Alternatively, professional waste disposal services can be utilized to handle the waste in compliance with local regulations. Proper protective equipment and safety measures are essential during handling and disposal to prevent exposure and contamination.