pyrazin-2-amine

Basic Information

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CAS Number

5049-61-6

Molecular Formula

C4H5N3

Molecular Weight

95.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

118.0 to 122.0 deg-C

Boiling Point

250.905°C at 760 mmHg

Flash Point

129.1℃

Refractive Index

1.5200 (estimate)

SMILES

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C1=CN=C(C=N1)N

InChI

InChI=1S/C4H5N3/c5-4-3-6-1-2-7-4/h1-3H,(H2,5,7)

InChIKey

XFTQRUTUGRCSGO-UHFFFAOYSA-N

LogP

0.05880000000000002

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

54.9

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Pyrazinamine
BDBM50354830
pyrazin-2-amine
EINECS 225-748-7
Pyrazine,2-dihydro-2-imino-
PS-9353
2-amino-pyrazine
HY-34068
CHEMBL1834089
AM1033
FT-0611270
1,2-Dihydro-2-iminopyrazine
AC-23436
NCGC00188272-01
MFCD00006137
5049-61-6
CL4536
2-aminopyrazin
AI3-60202
BCP13854
CS-D1606
Pyrazine, 2-amino-
BB 0248301
iminopyrazine
ENT 60202
BP-21335
pyrazineamine
DTXSID80198510
2 -aminopyrazine
NSC-13147
Pyrazine amine

MDL Number

MFCD00006137

Customs Code

2933990090

FAQ

What is pyrazin-2-amine (CAS: 5049-61-6)?

Pyrazin-2-amine (CAS: 5049-61-6) is a heterocyclic organic compound with the chemical formula C4H6N2. It is characterized by its pyrazine ring structure with an amino group at the 2nd position. This compound is a white solid with moderate solubility in polar solvents and is commonly used as an intermediate in pharmaceutical and chemical synthesis. Its molecular structure makes it valuable in the development of drugs and other functional chemicals.

What are the main uses of pyrazin-2-amine (CAS: 5049-61-6)?

Pyrazin-2-amine (CAS: 5049-61-6) is widely utilized in pharmaceuticals for synthesizing antifungal and antitubercular drugs, such as isoniazid. It also serves as a key intermediate in agrochemicals and industrial applications. In research, it is employed for creating derivatives with specific biological activities. Its versatility in chemical reactions makes it a critical component in drug development and material science.

Is pyrazin-2-amine (CAS: 5049-61-6) safe?

Pyrazin-2-amine (CAS: 5049-61-6) is generally considered safe when handled properly. However, it may cause mild irritation to the skin or respiratory system. Safety precautions include wearing protective gloves, goggles, and ensuring adequate ventilation. It is classified as a low-toxicity compound under standard regulatory guidelines, but direct contact or inhalation should be avoided to prevent adverse effects.

How should pyrazin-2-amine (CAS: 5049-61-6) be stored?

Pyrazin-2-amine (CAS: 5049-61-6) should be stored in a cool, dry place, away from moisture and direct light. It is best kept in airtight, sealed containers to maintain stability and prevent degradation. Storage conditions should avoid exposure to air and heat, ensuring it remains chemically inert. Proper storage prolongs its shelf life and ensures safety during handling and use.