5-Bromo-6-quinoxalinamine

Basic Information

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CAS Number

50358-63-9

Molecular Formula

C8H6BrN3

Molecular Weight

224.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

155.0 to 159.0 deg-C

SMILES

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C1=CC2=NC=CN=C2C(=C1N)Br

InChI

InChI=1S/C8H6BrN3/c9-7-5(10)1-2-6-8(7)12-4-3-11-6/h1-4H,10H2

InChIKey

IRAOSCSPAYZRJE-UHFFFAOYSA-N

LogP

1.9745

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

164

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

UNII-EU356DA5Q4
BRIMONIDINE TARTRATE IMPURITY B [EP IMPURITY]
AKOS015854599
6-amino-5-bromo quinoxaline
DTXSID701310968
CS-W022443
EN300-208308
FT-0650286
5-bromo-6-quinoxalinamine
BDBM626093
6-Amino-5-bromoquinoxaline
A7472
EU356DA5Q4
FT-0620934
5-BROMOQUINOXALIN-6-AMINE
5-Bromo-6-aminoquinoxaline
MFCD00799024
IRAOSCSPAYZRJE-UHFFFAOYSA-N
Z1269214504
Q-100562
SCHEMBL180196
6-AMINOCHINOXALIN-5-BROMCHINOXALIN
SY030906
Brimonidine tartrate impurity B [EP]
TS-03199
AC-193
6-Quinoxalinamine, 5-bromo-
50358-63-9
AM9700
134892-45-8
5-Bromoquinoxalin-6-Amine

MDL Number

MFCD00799024

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 5-Bromo-6-quinoxalinamine (CAS: 50358-63-9)?

5-Bromo-6-quinoxalinamine is a solid with a crystalline form. Its molecular weight is approximately 227.03 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is moderately reactive and can undergo substitution reactions at the bromine atom and the nitrogen atom. The compound is stable under normal conditions but should be stored in a dry, cool place away from direct sunlight and moisture.

How is 5-Bromo-6-quinoxalinamine (CAS: 50358-63-9) typically synthesized?

5-Bromo-6-quinoxalinamine is commonly synthesized by the bromination of 6-aminoquinoxaline in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction proceeds with high selectivity and yields up to 90%. The reaction conditions typically involve heating the mixture under an inert atmosphere to ensure purity and yield.

What industries use 5-Bromo-6-quinoxalinamine (CAS: 50358-63-9)?

5-Bromo-6-quinoxalinamine is used in various industries. It is a key intermediate in the pharmaceutical industry, where it is employed in the synthesis of antiviral and anticancer drugs. It is also used in the production of polymers for electronic applications, sensors, and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 5-Bromo-6-quinoxalinamine (CAS: 50358-63-9)?

When handling 5-Bromo-6-quinoxalinamine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a fume hood or properly ventilated area to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbents and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.