5-Bromo-6-quinoxalinamine(CAS: 50358-63-9)

5-Bromo-6-quinoxalinamine is a solid with a crystalline form. Its molecular weight is approximately 227.03 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is moderately reactive and can undergo substitution reactions at the bromine atom and the nitrogen atom. The compound is stable under normal conditions but should be stored in a dry, cool place away from direct sunlight and moisture.

5-Bromo-6-quinoxalinamine is commonly synthesized by the bromination of 6-aminoquinoxaline in the presence of a Lewis acid catalyst such as aluminum bromide. The reaction proceeds with high selectivity and yields up to 90%. The reaction conditions typically involve heating the mixture under an inert atmosphere to ensure purity and yield.

5-Bromo-6-quinoxalinamine is used in various industries. It is a key intermediate in the pharmaceutical industry, where it is employed in the synthesis of antiviral and anticancer drugs. It is also used in the production of polymers for electronic applications, sensors, and semiconductors due to its unique electronic properties.

When handling 5-Bromo-6-quinoxalinamine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a fume hood or properly ventilated area to minimize inhalation risks. In case of a spill, immediately clean up using appropriate absorbents and ensure proper disposal. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.