6-Hydroxynicotinic acid

Basic Information

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CAS Number

5006-66-6

Molecular Formula

C6H5NO3

Molecular Weight

139.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

>300 °C

Boiling Point

384℃ at 760 mmHg

Flash Point

186℃

Refractive Index

1.5423 (estimate)

SMILES

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C1=CC(=O)NC=C1C(=O)O

InChI

InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)

InChIKey

BLHCMGRVFXRYRN-UHFFFAOYSA-N

LogP

0.0731

Topological Polar Surface Area

70.16 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

239

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

s6285
F2124-1179
6-Hydroxynicotinate
2-hydroxy-5-pyridine carboxylic acid
Nicotinic acid,6-dihydro-6-oxo-
NSC8620
bmse000341
FT-0653628
CHEBI:16168
NSC 53377
2-hydroxy 5-pyridine carboxylic acid
6-hydroxy-pyridine-3-carboxylic acid
P10104
AKOS000120093
2-Hydroxypyridine-5-carboxylic acid
Nicotinic acid, 1,6-dihydro-6-oxo- (8CI)
Z104500708
15864-85-4
8PLJ71N310
Pyridin-2-one-5-carboxylic acid
SR-01000945209
2-Pyridone-5-carboxylic acid
3-Pyridinecarboxylic acid, 6-hydroxy-
HY-W001996
6-oxo-1,6-dihydropyridine-3-carboxylic acid
CHEMBL95293
1,6-dihydro-6-oxo-Nicotinic acid
AI3-52404
6-Hydroxy nicotinic acid
Q27098413
6-HYDROXYNICOTINIC ACID [USP-RS]

MDL Number

MFCD00006277

Customs Code

2933399090

FAQ

What is 6-Hydroxynicotinic acid (CAS: 5006-66-6)?

6-Hydroxynicotinic acid (CAS: 5006-66-6) is a pyridine derivative with the chemical formula C6H6NO3. It is a white crystalline solid that is soluble in water and organic solvents. This compound exhibits weak acidity due to the hydroxyl group and is commonly used in chemical research and pharmaceutical applications.

What are the main uses of 6-Hydroxynicotinic acid (CAS: 5006-66-6)?

6-Hydroxynicotinic acid (CAS: 5006-66-6) is primarily used in pharmaceuticals as a precursor for drug development, particularly in antidiabetic and anti-inflammatory treatments. It also finds applications in industrial chemistry for dye and pesticide synthesis, and in research for studying metabolic pathways and enzyme activity.

Is 6-Hydroxynicotinic acid (CAS: 5006-66-6) safe?

6-Hydroxynicotinic acid (CAS: 5006-66-6) is generally considered safe when handled properly. However, it may cause skin or eye irritation upon contact. Safety data sheets recommend using protective gloves, goggles, and ensuring adequate ventilation. It is not classified as a hazardous substance under standard regulations but should follow general chemical safety practices.

How should 6-Hydroxynicotinic acid (CAS: 5006-66-6) be stored?

6-Hydroxynicotinic acid (CAS: 5006-66-6) should be stored in a cool, dry place at 25°C, protected from light. Keep in a sealed, airtight container to prevent moisture absorption and degradation. Ensure storage in a well-ventilated area to maintain stability and avoid exposure to incompatible materials.