Thymidine | CAS No. 50-89-5

Thymidine

Basic Information

View in Editor

CAS Number

50-89-5

Molecular Formula

C10H14N2O5

Molecular Weight

242.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

187-189oC

Boiling Point

385.05°C (rough estimate)

Water Solubility

SOLUBLE

Solubility

73.5 mg/mL

Refractive Index

1.584

Specific Rotation

18.6 º (c=3, H2O)

SMILES

View in Editor

Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

InChI

InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1

InChIKey

IQFYYKKMVGJFEH-XLPZGREQSA-N

LogP

-1.5142799999999992

Topological Polar Surface Area

104.54999999999998 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

381

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

-20℃

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

Sensitive to light

Synonyms & References

English

Thymidine
(1-[2-Deoxy-beta-D-ribofuranosyl]-5-methyluracil)
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-ribofuranosyl)-5-methyl-
2'-Deoxythymidine
5-Methyldeoxyuridine
beta-D-Ribofuranoside,thymine-1,2-deoxy-
Deoxythymidine
Dexoythymidine
DThyd
Thymine-2-desoxyriboside
Thyminedeoxyriboside
Uridine,2'-deoxy-5-methyl-
Beta-Thymidine
β-Thymidine
&szlig
-Thymidine
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-furan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-.β.-D-erythro-pentofuranosyl)-5-methyl-
THYMIDIN(RG)
1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluraci
1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
1-(2-Deoxy-β-D-ribofuranosyl)thymine
2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-.Beta.-D-erythro-pentofuranosyl)-5-methyl
2'-dT
b-Thymidine
DTHD
dT
SS-THYMIDINE
Thymidin
Thymine-2-deoxyriboside

MDL Number

MFCD00006537

FAQ

What is Thymidine (CAS: 50-89-5)?

Thymidine is a nucleoside composed of the sugar deoxyribose and the nitrogenous base thymine. It is a key component of DNA and has the chemical formula C10H12N2O5. Thymidine is a white crystalline solid that is soluble in water and has a melting point around 235°C. It is commonly used in biochemical research and has applications in molecular biology and pharmaceutical sciences.

What are the main uses of Thymidine (CAS: 50-89-5)?

Thymidine is primarily used in DNA research and synthesis, as it is a fundamental building block of genetic material. It also serves as a precursor in the production of antiviral and anticancer drugs. In the food industry, it is used as a stabilizer and nutritional additive. Additionally, it is employed in the manufacture of certain biochemical reagents and in analytical chemistry for nucleotide analysis.

Is Thymidine (CAS: 50-89-5) safe?

Thymidine is generally considered safe when handled properly, but it should be treated with caution. It has low toxicity, but prolonged exposure may cause skin and eye irritation. Safety standards recommend using personal protective equipment such as gloves and goggles. Proper ventilation and adherence to standard laboratory safety protocols are essential to ensure safe handling and minimize risks.

How should Thymidine (CAS: 50-89-5) be stored?

Thymidine should be stored in a cool, dry, and dark place to maintain its stability. It is best kept at temperatures below 25°C and with humidity levels below 60%. Storage in airtight containers away from light and moisture is recommended to prevent degradation. Avoid exposure to strong oxidizing agents and keep it in a well-ventilated area.