5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide

Basic Information

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CAS Number

50-65-7

Molecular Formula

C13H8Cl2N2O4

Molecular Weight

327.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

225-230oC

Boiling Point

424.5°C at 760 mmHg

Flash Point

210.5°C

Solubility

acetone: methanol: soluble50mg/mL (methanol:acetone (1:1))

Refractive Index

1.709

Vapor Pressure

0mmHg at 25°C

SMILES

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C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O

InChI

InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)

InChIKey

RJMUSRYZPJIFPJ-UHFFFAOYSA-N

LogP

log Kow = 10 @ pH 9.6

Complexity

404

Safety Information

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GHS Hazard Pictograms

H400

Hazard Statement

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Synonyms & References

English

Niclocide
HMS502D11
2',5-Dichlor-4'-nitro-salizylsaeureanilid
NSC178296
CCG-39641
Niclosamide Anhydrous
Tox21_300749
KBioSS_000719
Yomensan
Clonitralide (Salt/Mix)
NICLOSAMIDE ANHYDROUS [WHO-IP]
KBio2_003287
niclosamide
HMS3262N13
DB06803
5-chloranyl-N-(2-chloranyl-4-nitro-phenyl)-2-oxidanyl-benzamide
Fenasal
Niclosamida
N 3510
KBio3_001553
Niclosamide [USAN:INN:BAN]
Tredemine
N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid [German]
BAY-2353
SB19414
MFCD00057597
Tox21_500866
NCGC00015735-24
LS-144196
Nitrophenyl chlorsalicylamide
Prestwick2_000040

MDL Number

MFCD08593323

Customs Code

2924299090

FAQ

What is 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7)?

5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7) is a chlorinated aromatic compound with a benzamide functional group. Its chemical formula is C14H8Cl2N2O4, and it is typically a solid with low solubility in water. The molecule exhibits stability under normal conditions but may degrade upon prolonged exposure to light or heat.

What are the main uses of 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7)?

This compound is primarily used in pharmaceutical research as an intermediate for drug development, particularly in agrochemicals and insecticides. It also finds applications in organic synthesis and as a precursor for functionalized aromatic compounds. Its utility stems from the reactivity of the hydroxyl and amide groups, making it valuable in creating complex molecules for scientific studies.

Is 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7) safe?

Safety of 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7) depends on exposure conditions. It may exhibit moderate toxicity upon inhalation or skin contact, so protective measures like gloves and ventilation are recommended. Proper handling and disposal should follow OSHA and EPA guidelines to ensure safety in industrial and laboratory settings.

How should 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7) be stored?

Store 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide (CAS: 50-65-7) in a cool, dry place (ideally below 25°C), away from light. Maintain humidity levels below 60% and use airtight containers to prevent moisture absorption. Avoid contact with incompatible materials and ensure proper labeling for safe handling and storage.