10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine

Basic Information

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CAS Number

50-52-2

Molecular Formula

C21H26N2S2

Molecular Weight

370.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

72-74°

Boiling Point

230°C at 0.02 MM HG

Flash Point

265.665°C

Refractive Index

1.5800 (estimate)

SMILES

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CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC

InChI

InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3

InChIKey

KLBQZWRITKRQQV-UHFFFAOYSA-N

LogP

log Kow = 5.90

pKa

9.5(at 25℃)

Topological Polar Surface Area

6.48 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

432

Safety Information

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Toxicity

LD50 orally in rats: 995 ±39 mg/kg (Goldenthal)

Synonyms & References

English

KBio1_000066
Biomol-NT_000017
cMAP_000015
Thioridazine prolongatum
10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine
KLBQZWRITKRQQV-UHFFFAOYSA-N
Ridazine
50-52-2
107388-89-6
THIORIDAZINE [USAN]
Thioridazinum
DivK1c_000066
SCHEMBL12434241
Phenothiazine, 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)-
BDBM50002338
NCGC00016059-05
NCGC00016059-24
10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl) ethyl]-2-(methylthio)-
AB00053553_18
NSC186060
Thioridazin
KBioGR_000791
Novoridazine (TN)
Thioril
C21H26N2S2
Thioridazine, prolongatum
Spectrum5_001062
HY-B0965A
Spectrum3_000585
DTXCID403656
Metlaril

MDL Number

MFCD00242875

FAQ

What regulatory guidelines apply to 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2)?

10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2) is regulated under GHS classification as a hazardous substance. It is subject to REACH regulations for identification, labeling, and safety data sheets. FDA and EPA have specific requirements regarding its use in pharmaceuticals and pesticides, focusing on safety, environmental impact, and proper disposal.

Are there alternatives to 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2) in synthesis?

Alternatives to 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2) include related phenothiazine derivatives such as thiophenothiazines and piperidines. Common alternative reagents for synthesis include piperidine and its derivatives, often used in synthesizing similar heterocyclic compounds.

What is the market or research trend for 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2)?

The market and research trend for 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2) focuses on its potential in pharmaceutical applications, particularly in the development of antipsychotic drugs and mood stabilizers. Recent research trends include investigating its efficacy and side effects, as well as exploring its use in other therapeutic areas such as neurodegenerative diseases.

How should waste containing 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2) be handled?

Waste containing 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine (CAS: 50-52-2) should be collected and disposed of in accordance with local regulations. Proper waste management involves neutralization or incineration, followed by safe disposal. Environmental protection measures include minimizing exposure to water sources and ensuring the waste is handled by professionals with appropriate licenses and equipment.