4-Hydroxy-3-hexanone

Basic Information

View in Editor

CAS Number

4984-85-4

Molecular Formula

C6H12O2

Molecular Weight

116.16 g/mol

Basic Physical Properties

Melting Point

-3.75°C (estimate)

Boiling Point

167°C

Flash Point

59.3±11.0 ºC,

Refractive Index

1.4340 (589.3 nm 21 ºC)

SMILES

View in Editor

CCC(O)C(=O)CC

InChI

InChI=1S/C6H12O2/c1-3-5(7)6(8)4-2/h5,7H,3-4H2,1-2H3

InChIKey

SKCYVGUCBRYGTE-UHFFFAOYSA-N

LogP

0.7363999999999999

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

78.6

Safety Information

View Safety Information

GHS Hazard Pictograms

H226

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Synonyms & References

English

3-Hexanone, 4-hydroxy-
Propioin
-Hexanone, 4-hydroxy-
3-Hexanone,4-hydroxy
3-Hydroxy-4-hexanone
4-Hydroxy-3-hexanone
4-hydroxy-4-hexanone
4-Hydroxy-hexan-3-on
4-hydroxy-hexan-3-one
4-Hydroxyhexane-3-one
PROPIONOIN
Propionoine
Propyroin
Ethyl alpha-hydroxypropyl ketone
NSC 23087
Propionoin

MDL Number

MFCD00043572

Customs Code

2914400090

FAQ

What are the physical and chemical properties of 4-Hydroxy-3-hexanone (CAS: 4984-85-4)?

4-Hydroxy-3-hexanone (CAS: 4984-85-4) is a colorless or slightly yellow liquid with a boiling point of 136-137°C and a molecular weight of approximately 124.16 g/mol. It has a solubility of up to 80 g/L in water and is miscible with alcohol. The compound is moderately reactive, typically showing basic properties due to the hydroxyl group.

How is 4-Hydroxy-3-hexanone (CAS: 4984-85-4) typically synthesized?

4-Hydroxy-3-hexanone can be synthesized through the reaction of hexanal with sodium hydroxide, followed by dehydration. This process yields 4-hydroxy-3-hexanone with a high yield. The reaction is typically conducted in aqueous medium with the use of sodium hydroxide as a catalyst, ensuring good selectivity and high purity.

What industries use 4-Hydroxy-3-hexanone (CAS: 4984-85-4)?

4-Hydroxy-3-hexanone (CAS: 4984-85-4) is used in various industries including pharmaceuticals for the synthesis of certain drugs, as a solvent in polymer manufacturing, and in the production of sensors and semiconductors for its specific chemical and physical properties.

What precautions should be taken when handling 4-Hydroxy-3-hexanone (CAS: 4984-85-4)?

When handling 4-Hydroxy-3-hexanone (CAS: 4984-85-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate methods, and the substance should be stored in a cool, dry location away from heat sources. Always refer to the Safety Data Sheet (SDS) for specific handling and storage guidelines.