3-Piperidinecarboxylic acid

Basic Information

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CAS Number

498-95-3

Molecular Formula

C6H11NO2

Molecular Weight

129.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

261 °C (dec.)

Boiling Point

265.8℃ at 760 mmHg

Water Solubility

Soluble in water

Flash Point

114.5℃

Solubility

water: soluble50mg/mL, clear, colorless to faintly yellow

Refractive Index

1.4587 (estimate)

SMILES

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C1CC(CNC1)C(=O)O

InChI

InChI=1S/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)

InChIKey

XJLSEXAGTJCILF-UHFFFAOYSA-N

LogP

0.07060000000000005

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

114

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3-Piperidinecarboxylic acid
SB41071
(+/-)-3-piperidine carboxylic acid
3-piperidinic acid
NCGC00260726-01
BSPBio_000920
Q-200393
NCGC00024510-02
CHEBI:116931
SY009080
nipecotic acid
A16064
h-dl-nip-oh
SR-01000075612-1
SMR000059031
(y)-Nipecotic acid
Piperidine-3-carboxylic acid
DivK1c_000148
(+/-)-beta-Homoproline
BDBM50003624
SB10229
Spectrum5_001412
SCHEMBL85677
Spectrum2_001184
hexahydronicotinic acid
UNII-1U1QTN40SY
HMS2235L11
MLS000069598
SDCCGSBI-0050030.P003
Nipecotic acid, 98%
NCGC00014992-14

MDL Number

MFCD00005992

Customs Code

29339900

FAQ

What is 3-Piperidinecarboxylic acid (CAS: 498-95-3)?

3-Piperidinecarboxylic acid (CAS: 498-95-3) is a piperidine derivative with the chemical formula C7H13NO2. It is a colorless liquid, commonly used in organic synthesis, and exhibits solubility in water and organic solvents. Its structure includes a six-membered piperidine ring fused with a carboxylic acid group, making it a key intermediate in pharmaceutical and industrial applications.

What are the main uses of 3-Piperidinecarboxylic acid (CAS: 498-95-3)?

3-Piperidinecarboxylic acid (CAS: 498-95-3) is widely used in pharmaceuticals as a building block for drugs targeting neurological disorders. It also serves in industrial chemistry for polymer science and as a precursor for other organic compounds. In research, it is employed in the synthesis of bioactive molecules and as a reagent in chemical processes. Its applications span across medicinal, agricultural, and materials science fields.

Is 3-Piperidinecarboxylic acid (CAS: 498-95-3) safe?

3-Piperidinecarboxylic acid (CAS: 498-95-3) is generally safe when handled properly. It may cause mild skin or eye irritation, so protective gloves, goggles, and ventilation are recommended. Safety data sheets (SDS) classify it under specific hazard categories, and adherence to OSHA and EPA guidelines ensures safe use in laboratories and industrial settings.

How should 3-Piperidinecarboxylic acid (CAS: 498-95-3) be stored?

3-Piperidinecarboxylic acid (CAS: 498-95-3) should be stored in a cool, dry place away from light, ideally at 2-8°C. It requires airtight, glass containers to prevent moisture absorption and degradation. Avoid exposure to heat and air to maintain stability, and ensure proper labeling for safe handling and storage conditions.