Lurbinectedin | CAS No. 497871-47-3

Lurbinectedin

Basic Information

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CAS Number

497871-47-3

Molecular Formula

C41H44N4O10S

Molecular Weight

784.89 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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Cc1cc2c(c(c1OC)O)[C@@H]3[C@@H]4[C@H]5c6c(c7c(c(c6OC(=O)C)C)OCO7)[C@@H](N4[C@H]([C@H](C2)N3C)O)COC(=O)[C@@]8(CS5)c9c(c1cc(ccc1[nH]9)OC)CCN8

InChI

InChI=1S/C41H44N4O10S/c1-17-11-20-12-25-39(48)45-26-14-52-40(49)41(38-22(9-10-42-41)23-13-21(50-5)7-8-24(23)43-38)15-56-37(31(45)30(44(25)4)27(20)32(47)33(17)51-6)29-28(26)36-35(53-16-54-36)18(2)34(29)55-19(3)46/h7-8,11,13,25-26,30-31,37,39,42-43,47-48H,9-10,12,14-16H2,1-6H3/t25-,26-,30+,31+,37+,39-,41+/m0/s1

InChIKey

YDDMIZRDDREKEP-HWTBNCOESA-N

LogP

4.188940000000002

Topological Polar Surface Area

164.27999999999997 Å²

Hydrogen Bond Donor/Acceptor

4 / 14

Complexity

1530

Synonyms & References

English

Lurbinectedin
PM01183
PM-01183
2CN60TN6ZS
PM 01183
Zepzelca
Lurbinectedin [USAN:INN]
GTPL10681
WHO 9397
PM1183
s9603
DB12674
J3.5

MDL Number

MFCD22665743

FAQ

What is Lurbinectedin (CAS: 497871-47-3)?

Lurbinectedin (CAS: 497871-47-3) is a semisynthetic marine natural product with a unique chemical structure. It is used in the treatment of small cell lung cancer (SCLC).

What are the main uses of Lurbinectedin (CAS: 497871-47-3)?

Lurbinectedin (CAS: 497871-47-3) is primarily used for the treatment of patients with small cell lung cancer who have progressed or relapsed after at least one prior chemotherapy regimen.

Is Lurbinectedin (CAS: 497871-47-3) safe?

Lurbinectedin (CAS: 497871-47-3) has potential safety concerns, including serious side effects such as neutropenia, severe skin reactions, and liver toxicity. It is essential to follow medical guidance and take necessary precautions.

How should Lurbinectedin (CAS: 497871-47-3) be stored?

Lurbinectedin (CAS: 497871-47-3) should be stored at 2-8°C in a refrigerator, protected from light, and in its original container. It should be protected from excessive heat and moisture.