Arbutin | CAS No. 497-76-7

Arbutin

Basic Information

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CAS Number

497-76-7

Molecular Formula

C12H16O7

Molecular Weight

272.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

197.0 to 202.0 deg-C

Boiling Point

561.6°C at 760 mmHg

Water Solubility

10-15 g/100 mL at 20 ºC

Flash Point

293.4ºC

Solubility

H2O: 50 mg/mL hot, clear

Refractive Index

-65.5 ° (C=4, H2O)

Vapor Pressure

2.30X10-12 mm Hg at 25 °C (est)

Specific Rotation

-64 º (c=3)

SMILES

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OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1

InChIKey

BJRNKVDFDLYUGJ-RMPHRYRLSA-N

LogP

-1.4291000000000003

Topological Polar Surface Area

119.61000000000001 Å²

Hydrogen Bond Donor/Acceptor

5 / 7

Complexity

279

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Stability

Stable. Hygroscopic - store under dry nitrogen.

Sensitiveness

Hygroscopic

Synonyms & References

English

Arbutin
4-HYDROXYPHENYL-BETA-D-GLUCOPYRANOSIDE
ARBUTOSIDE
B-D-GLUCOPYRANOSIDE, 4-HYDROXYPHENYL
HYDROQUINONE-BETA-D-GLUCOPYRANOSIDE
HYDROQUINONE-BETA-D-GLUCOSIDE
P-ARBUTIN
URSIN
UVASOL
4-hydroxyphenyl-beta-d-glucopyranosid
beta-arbutin
Arbutosie
Arbutus extract
Uresol
ARBUTIN CRYSTALLINE SYNTHETIC
ARBUTIN:B-D-GLUCOPYRANOSIDE, 4-HYDROXYPHENYL,
Hydroquinone glucose
.beta.-D-Glucopyranoside, 4-hydroxyphenyl
4-hydroxyphenyl-á-d-glucopyranoside
hydroquinone O-β-D-glucopyranoside
ARBUTIN(P) PrintBack
ARBUTIN(RG)
4-Hydroxyphenyl Beta-D-Glucopyranoside
4-Hydroxyphenyl β-D-Glucopyranoside
4-Hydroxyphenyl-β-D-glucopyranoside
4-Hydroxyphenyl-β-D-glucopyranosidep
hydroquinone O-beta-D-glucopyranoside
Hydroquinoneβ-D-glucopyranoside
Hydroquinone-β-D-glucopyranoside
Hydroquinone-β-D-glucoside
β-Arbutin

MDL Number

MFCD00016915

Customs Code

29389090

FAQ

What is Arbutin (CAS: 497-76-7)?

Arbutin (CAS: 497-76-7) is a natural compound derived from bearberry. It has the chemical formula C13H10O6 and is known for its mild exfoliating properties. Arbutin is a glycoside that acts as a skin-lightening agent by inhibiting melanin production. It is commonly used in skincare products and is considered safe when used in appropriate concentrations.

What are the main uses of Arbutin (CAS: 497-76-7)?

Arbutin (CAS: 497-76-7) is widely used in the cosmetic industry for its skin-brightening effects. It is found in skincare products such as creams, serums, and toners. Additionally, it has applications in pharmaceuticals for treating hyperpigmentation and in research for studying skin health and melanin regulation. Its natural origin makes it a popular choice for eco-friendly formulations.

Is Arbutin (CAS: 497-76-7) safe?

Arbutin (CAS: 497-76-7) is generally considered safe when used in recommended concentrations. It has low toxicity and is well-tolerated by most skin types. However, proper handling and use are important to avoid potential irritation. Safety standards ensure its use in cosmetics and pharmaceuticals is regulated for consumer protection.

How should Arbutin (CAS: 497-76-7) be stored?

Arbutin (CAS: 497-76-7) should be stored in a cool, dry place away from direct sunlight. It is best kept in airtight containers to prevent moisture exposure. Maintaining stable temperature and humidity levels helps preserve its potency and effectiveness. Avoid storing it in areas with high heat or air circulation to ensure long-term quality.