2-Bromo-4-fluorophenol

Basic Information

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CAS Number

496-69-5

Molecular Formula

C6H4BrFO

Molecular Weight

191 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

43.0 to 46.0 deg-C

Boiling Point

89°C/0.8mmHg

Refractive Index

1.554

SMILES

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C1=CC(=C(C=C1F)Br)O

InChI

InChI=1S/C6H4BrFO/c7-5-3-4(8)1-2-6(5)9/h1-3,9H

InChIKey

MEYRABVEYCFHHB-UHFFFAOYSA-N

LogP

2.2938

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

99.1

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

EN300-21341
InChI=1/C6H4BrFO/c7-5-3-4(8)1-2-6(5)9/h1-3,9H
DTXSID70345556
NS00123416
AM62012
HY-W003971
2-Bromo-4-fluorophenol, 98%
PS-8366
AC-3753
MFCD00010614
2-bromo4-fluoro-phenol
MEYRABVEYCFHHB-UHFFFAOYSA-
BCP21692
A855773
496-69-5
cyclohexylethylcarbamoylchloride
FT-0611453
CS-W003971
Phenol, 2-bromo-4-fluoro-
2-bromo-4-fluoro phenol
SY021807
B1555
A1722
F0001-1292
2-bromo-4-flourophenol
J-508298
2-Bromo-4-fluorophenol
2-bromo-4-fluoro-phenol
AKOS000120655
SCHEMBL91229
2-Brom-4-fluor-phenol

MDL Number

MFCD00010614

Customs Code

2908199090

FAQ

What are the physical and chemical properties of 2-Bromo-4-fluorophenol (CAS: 496-69-5)?

2-Bromo-4-fluorophenol (CAS: 496-69-5) is a crystalline solid with a molecular weight of 190.02 g/mol. It has a solubility of 0.5 g/L in water and moderate solubility in organic solvents like ethanol and acetone. It is moderately reactive, particularly towards nucleophiles and reducing agents. It is not flammable but should be handled with caution due to its potential reactivity.

How is 2-Bromo-4-fluorophenol (CAS: 496-69-5) typically synthesized?

2-Bromo-4-fluorophenol (CAS: 496-69-5) is typically synthesized via electrophilic aromatic substitution. A common method involves the reaction of 4-fluorophenol with bromine in the presence of a Lewis acid catalyst, such as aluminum bromide, to promote the electrophilic bromination.

What industries use 2-Bromo-4-fluorophenol (CAS: 496-69-5)?

2-Bromo-4-fluorophenol (CAS: 496-69-5) is used in various industries, including pharmaceuticals, where it serves as an intermediate in the synthesis of certain drugs. It also finds applications in the production of dyes, pigments, and as a precursor in the development of materials for sensors and semiconductors.

What precautions should be taken when handling 2-Bromo-4-fluorophenol (CAS: 496-69-5)?

When handling 2-Bromo-4-fluorophenol (CAS: 496-69-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for specific recommendations on handling and storage.