2-Bromo-4-fluorophenol(CAS: 496-69-5)

2-Bromo-4-fluorophenol (CAS: 496-69-5) is a crystalline solid with a molecular weight of 190.02 g/mol. It has a solubility of 0.5 g/L in water and moderate solubility in organic solvents like ethanol and acetone. It is moderately reactive, particularly towards nucleophiles and reducing agents. It is not flammable but should be handled with caution due to its potential reactivity.

2-Bromo-4-fluorophenol (CAS: 496-69-5) is typically synthesized via electrophilic aromatic substitution. A common method involves the reaction of 4-fluorophenol with bromine in the presence of a Lewis acid catalyst, such as aluminum bromide, to promote the electrophilic bromination.

2-Bromo-4-fluorophenol (CAS: 496-69-5) is used in various industries, including pharmaceuticals, where it serves as an intermediate in the synthesis of certain drugs. It also finds applications in the production of dyes, pigments, and as a precursor in the development of materials for sensors and semiconductors.

When handling 2-Bromo-4-fluorophenol (CAS: 496-69-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Refer to the Safety Data Sheet (SDS) for specific recommendations on handling and storage.