2-[(2-Nitrophenyl)amino]ethanol

Basic Information

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CAS Number

4926-55-0

Molecular Formula

C8H10N2O3

Molecular Weight

182.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

71.0 to 75.0 deg-C

Boiling Point

376.6 ºC at 760 mmHg

Density

1.352

Flash Point

181.6 ºC

Refractive Index

1.64

SMILES

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OCCNc1ccccc1[N+](=O)[O-]

InChI

InChI=1S/C8H10N2O3/c11-6-5-9-7-3-1-2-4-8(7)10(12)13/h1-4,9,11H,5-6H2

InChIKey

LFOUYKNCQNVIGI-UHFFFAOYSA-N

LogP

1.59520

Complexity

169

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-((2-Nitrophenyl)amino)ethanol
2-[(2-Nitrophenyl)amino]ethanol
HC-Yelow 2
2-(2-nitroanilino)ethanol
2-Nitro-N-Hydroxyethyl Aniline
N-(2-Hydroxyethyl)-2-nitroaniline
2-Nitro-N-(2-hydroxyethyl)aniline
HC Yellow 2
N-(2-Nitrophenyl)ethanolamine
2-Nitro-N-(hydroxyethyl)aniline
Ethanol, 2-[(2-nitrophenyl)amino]-
HC Yellow no. 2
Ethanol, 2-(o-nitroanilino)-
N-(2-Hydroxyethyl)-o-nitroaniline
N-Hydroxyethyl-2-nitroaniline
9FVT2KMV9O
2-[(2-nitrophenyl)amino]ethan-1-ol
LFOUYKNCQNVIGI-UHFFFAOYSA-N
Ethanol, 2-((2-nitrophenyl)amino)-

MDL Number

MFCD00239475

Customs Code

2922199090

FAQ

What are the physical and chemical properties of 2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0)?

2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0) is a crystalline solid with a molecular weight of approximately 222.13 g/mol. It has a pKa around 5.5 and is moderately soluble in water. This compound is relatively reactive, especially towards nucleophilic substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place to prevent hydrolysis.

How is 2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0) typically synthesized?

2-[(2-Nitrophenyl)amino]ethanol is commonly synthesized via the reaction of 2-nitrophenol with ethanol in the presence of a base such as sodium hydroxide. The process typically involves heating the mixture to reflux, followed by workup and purification steps. High selectivity and good yield are achievable with this method.

What industries use 2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0)?

2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0) is used in the pharmaceutical industry for synthesizing various compounds. It is also employed in the production of dyes, organic semiconductors, and as a precursor in polymer synthesis. Its application in sensors and as a reagent in analytical chemistry is also notable.

What precautions should be taken when handling 2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0)?

When handling 2-[(2-Nitrophenyl)amino]ethanol (CAS: 4926-55-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of spills, immediately clean up with appropriate absorbent materials and wash the area with water. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage recommendations.