4-Quinazolinol

Basic Information

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CAS Number

491-36-1

Molecular Formula

C8H6N2O

Molecular Weight

146.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

215.0 to 220.0 deg-C

Boiling Point

303.5°C at 760 mmHg

Water Solubility

Soluble in DMSO (100 mM), ethanol, methanol, and water (10 mM).

Flash Point

137.3 °C

Solubility

Acetontrile

Refractive Index

1.4900 (estimate)

SMILES

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C1=CC=C2C(=C1)C(=O)NC=N2

InChI

InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)

InChIKey

QMNUDYFKZYBWQX-UHFFFAOYSA-N

LogP

0.9231

Topological Polar Surface Area

45.75 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

200

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Storage Conditions

2-8℃

Sensitiveness

Hygroscopic

Synonyms & References

English

HMS3268P19
CC65A28C-4F60-4D22-81DC-326D7F32EEE0
JBH
DTXSID8049412
4(3H)?-?Quinazolinone
4-Quinazolinol(9ci)
HMS2267F20
CHEBI:113558
3,4-dihydroquinazolin4-one
4pnn
BB 0242096
EU-0000466
SY001011
W-200389
H0803
4-Quinazolinol
A7361
NCGC00092327-01
4-(3h)-quinazolinone
3H-Quinazolin-4-one
GEO-01561
NS00031860
UNII-84JOT4EY5X
DTXCID7029372
C-201-0583
NCGC00092327-05
84JOT4EY5X
HMS1768L21
3-hydro-4-quinazolinone
STR01100
4-Hydroxyquinazoline, 98%

MDL Number

MFCD00511302

Customs Code

29335995

FAQ

What is 4-Quinazolinol (CAS: 491-36-1)?

4-Quinazolinol is a heterocyclic organic compound with the chemical formula C8H7N3O. It is characterized by a fused benzene and pyrimidine ring system and contains a hydroxyl group at the 4-position. This compound is known for its use in pharmaceutical research and exhibits various chemical properties, including solubility in polar solvents and reactivity in organic synthesis.

What are the main uses of 4-Quinazolinol (CAS: 491-36-1)?

4-Quinazolinol is primarily used in pharmaceutical research as a building block for the synthesis of drugs targeting neurological and cardiovascular disorders. It also finds applications in organic chemistry for developing new materials and in research related to medicinal chemistry and drug discovery.

Is 4-Quinazolinol (CAS: 491-36-1) safe?

4-Quinazolinol is generally considered safe when handled properly, but it may have mild toxic effects if ingested or inhaled in large quantities. Safety precautions include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. It is important to follow standard chemical safety protocols and regulatory guidelines for handling this compound.

How should 4-Quinazolinol (CAS: 491-36-1) be stored?

4-Quinazolinol should be stored in a cool, dry, and dark place, ideally at 2-8°C. It should be kept in a sealed, airtight container to prevent moisture and contamination. Avoid exposure to light and ensure it is stored away from incompatible substances to maintain its stability and potency.