4-Methylquinoline

Basic Information

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CAS Number

491-35-0

Molecular Formula

C10H9N

Molecular Weight

143.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

9-10 °C

Boiling Point

265°C

Refractive Index

n20/D 1.620(lit.)

SMILES

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Cc1ccnc2ccccc12

InChI

InChI=1S/C10H9N/c1-8-6-7-11-10-5-3-2-4-9(8)10/h2-7H,1H3

InChIKey

MUDSDYNRBDKLGK-UHFFFAOYSA-N

LogP

2.5432200000000007

pKa

5.67(at 20℃)

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

133

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Light Sensitive

Synonyms & References

English

Lepidine
4-Lepidine
4-METHYLCHINOLINE
4-METHYLQUINOLINE
4-methyl-quinolin
Cincholepidine
gamma-Methylquinoline
-Methylquinoline
Quinoline,4-methyl-
4-METHYLQUINUOLINE
4-Methylquinoline, Lepidine
Lepidin
p-Methylquinoline
Quinoline,4-methyl
4-Methylquinoline

MDL Number

MFCD00006784

FAQ

What regulatory guidelines apply to 4-Methylquinoline (CAS: 491-35-0)?

4-Methylquinoline (CAS: 491-35-0) is regulated under the Globally Harmonized System (GHS) as a carcinogen category 1 and requires proper handling, storage, and disposal. In the European Union, it must comply with REACH regulations. In the USA, it is subject to FDA and EPA guidelines, particularly for industrial and consumer products.

Are there alternatives to 4-Methylquinoline (CAS: 491-35-0) in synthesis?

For synthesis, 4-Methylquinoline (CAS: 491-35-0) can be replaced by its analogs or other quinoline derivatives such as 5-Methylquinoline or 2-Methylquinoline. Alternative reagents like 4-chloroquinoline or 4-aminopiperidine can also be considered depending on the specific reaction conditions and desired product.

What is the market or research trend for 4-Methylquinoline (CAS: 491-35-0)?

Market demand for 4-Methylquinoline (CAS: 491-35-0) has seen steady growth due to its application in pharmaceuticals and dyes. Research trends include exploring its potential in organic semiconductors and catalysis. However, due to its carcinogenicity, there is increasing focus on developing safer alternatives.

How should waste containing 4-Methylquinoline (CAS: 491-35-0) be handled?

Waste containing 4-Methylquinoline (CAS: 491-35-0) should be collected in sealed containers and disposed of according to local regulations. Preferably, it should be incinerated or treated through professional waste disposal services. Proper environmental protection measures, including containment and filtration, must be followed to prevent contamination.