N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide | CAS No. 488832-69-5

N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide

Basic Information

CAS Number

488832-69-5

Molecular Formula

C19H20N4O2S2

Molecular Weight

400.53 g/mol

AD

Basic Physical Properties

CN(C(=S)C1=CC=CC=C1)NC(=O)CC(=O)NN(C)C(=S)C2=CC=CC=C2

InChI

InChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25)

InChIKey

BKJIXTWSNXCKJH-UHFFFAOYSA-N

LogP

2.0539000000000005

Topological Polar Surface Area

64.68 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

510

Synonyms & References

English

  • SW219775-1
  • D08909
  • BCP9000639
  • N'1,N'3-dibenzenecarbothioyl-N'1,N'3-dimethylpropanedihydrazide
  • SB17208
  • H11160
  • Q5359460
  • NCGC00183656-01
  • STA-4783
  • N'1,N'3-dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide
  • GSK-842879A
  • Elesclomol
  • NCGC00183656-02
  • EX-A602
  • N-malonyl-bis (N'-methyl-N'-thiobenzoyl hydrazide)
  • BRD-K82135108-001-01-9
  • HMS3868I03
  • STA4783
  • Elesclomol [USAN]
  • NSC-174939
  • MLS006011164
  • N inverted exclamation mark 1,N inverted exclamation mark 3-Dimethyl-N inverted exclamation mark 1,N inverted exclamation mark 3-di(phenylcarbonothioyl)malonohydrazide
  • HY-12040
  • CCG-264795
  • A23836
  • BKJIXTWSNXCKJH-UHFFFAOYSA-N
  • 1-N',3-N'-bis(benzenecarbonothioyl)-1-N',3-N'-dimethylpropanedihydrazide
  • elesclomolum
  • NS00068736
  • ELESCLOMOL [MART.]
  • Elesclomol [USAN:INN]

MDL Number

MFCD12911784

FAQ

What are the physical and chemical properties of N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5)?

N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5) is a crystalline compound with a molecular weight of approximately 506.36 g/mol. It is slightly soluble in common organic solvents like methanol and acetone. This compound is known for its high reactivity, particularly in nucleophilic substitution reactions. It is often used in chemical synthesis due to its stability under certain conditions and its ability to form stable intermediates.

How is N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5) typically synthesized?

N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5) is typically synthesized through a multi-step process involving the reaction of malonohydrazide with phenylcarbonothioic acid. The process requires careful control of temperature and pH to achieve high yields. Commonly, this involves the use of anhydrous solvents and mild to moderate heating to facilitate the reaction. The product is usually purified by recrystallization from appropriate solvents.

What industries use N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5)?

N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5) is primarily used in the pharmaceutical and polymer industries. In pharmaceuticals, it serves as an intermediate in the synthesis of certain drugs. In polymers, it is used as a stabilizer or cross-linking agent. Its use in sensors and semiconductors is also being explored for its unique chemical properties.

What precautions should be taken when handling N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5)?

When handling N'~1~,N'~3~-Dimethyl-N'~1~,N'~3~-bis(phenylcarbonothioyl)malonohydrazide (CAS: 488832-69-5), it is essential to wear proper personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using an appropriate absorbent material, followed by thorough washing with water. Always refer to the Material Safety Data Sheet (MSDS) for specific safety and handling procedures.

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