7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one

Basic Information

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CAS Number

486-21-5

Molecular Formula

C11H10O5

Molecular Weight

222.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

146-149°C

Boiling Point

452.1°C at 760 mmHg

Density

1.3580

Flash Point

183.2°C

Solubility

Methanol,Ethyl Acetate,Acetontrile,Water,DMSO,DMF

Refractive Index

1.587

SMILES

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COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)O

InChI

InChI=1S/C11H10O5/c1-14-7-5-6-3-4-8(12)16-10(6)11(15-2)9(7)13/h3-5,13H,1-2H3

InChIKey

HOEVRHHMDJKUMZ-UHFFFAOYSA-N

LogP

1.5157999999999998

Topological Polar Surface Area

68.9 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

301

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Synonyms & References

English

CS-0009797
7-hydroxy-6,8-dimethoxy-chromen-2-one;Isofraxidin
Calycanthogenol
CCG-266730
HY-N0774
Coumarin, 7-hydroxy-6,8-dimethoxy-
UNII-304915F056
NS00134341
Q15426264
5-18-04-00332 (Beilstein Handbook Reference)
NSC 324637
CHEMBL451518
s9240
FT-0688350
7-Hydroxy-6,8-dimethoxy-2H-1-benzopyran-2-one
A827571
AKOS000278010
Isofraxidin, analytical standard
BRN 0202652
HOEVRHHMDJKUMZ-UHFFFAOYSA-N
BS-42209
486-21-5
AC-8051
Isofraxidin ,(S)
Umbelliferone, 6,8-dimethoxy-
7-hydroxy-6,8-dimethoxychromen-2-one
7-hydroxy-6,8-dimethoxy-2H-chromen-2-one
ISOFRAXIDIN B814484K143
CHEBI:81121
DTXSID70197557
MFCD00221757

MDL Number

MFCD00221757

FAQ

What is 7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5)?

7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5) is a flavone derivative commonly used in organic chemistry. It has the molecular formula C12H10O5 and is known for its yellow crystalline appearance. This compound exhibits moderate solubility in polar solvents and is often utilized as a starting material in the synthesis of various bioactive compounds and pharmaceuticals.

What are the main uses of 7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5)?

7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5) is primarily used in pharmaceutical research for developing anti-inflammatory and antioxidant agents. It also serves as an intermediate in the production of agrochemicals and is studied for its potential applications in drug discovery and chemical synthesis. Its structure makes it valuable in creating derivatives with enhanced biological activity.

Is 7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5) safe?

7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5) is generally considered safe when handled properly. However, it should be treated with care, as it may cause skin or eye irritation. Safety precautions include using personal protective equipment (PPE) like gloves and safety goggles, and working in a well-ventilated area. It is classified as a low-toxicity compound under standard safety guidelines.

How should 7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5) be stored?

7-Hydroxy-6,8-dimethoxy-2H-chromen-2-one (CAS: 486-21-5) should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is best kept in a sealed, airtight container to prevent moisture absorption and degradation. Avoid exposure to direct light and extreme temperatures to maintain its stability and potency over time.