1-Isoindolinone

Basic Information

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CAS Number

480-91-1

Molecular Formula

C8H7NO

Molecular Weight

133.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

149.0 to 153.0 deg-C

Boiling Point

337°C

Flash Point

220.2°C

Refractive Index

1.5282 (estimate)

SMILES

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C1C2=CC=CC=C2C(=O)N1

InChI

InChI=1S/C8H7NO/c10-8-7-4-2-1-3-6(7)5-9-8/h1-4H,5H2,(H,9,10)

InChIKey

PXZQEOJJUGGUIB-UHFFFAOYSA-N

LogP

0.93

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

155

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

HY-W004767
NSC-3689
SCHEMBL1144058
1-Isoindolinone
CS-W004767
EN300-35925
Q27144540
SCHEMBL15580117
2,3-DIHYDRO-1H-ISOINDOL-1-ONE
1H-Isoindol-1-one,2,3-dihydro-
Benzo(3,4)pyrrolidone-2
A7325
2,3-dihydroisoindol-1-one
isoindolinone
DTXSID30197391
AB13096
SS-6041
1-oxo-isoindoline
dihydro-isoindol-1-one
1-Isoindolinone #
Phthalimidine
AM20040544
isoindolin-1-one;1-Isoindolinone
AKOS005173935
SY020116
2,3-Dihydro-isoindol-1-one
isoindolin-1-one
1H-Isoindol-1-one, 2,3-dihydro-
1-Isoindolinone, AldrichCPR
BB 0258318
I1064

MDL Number

MFCD03085939

Customs Code

2933790090

FAQ

What regulatory guidelines apply to 1-Isoindolinone (CAS: 480-91-1)?

1-Isoindolinone (CAS: 480-91-1) is subject to various regulatory guidelines. In the European Union, it falls under the REACH regulation, which requires registration, evaluation, authorization, and restriction of chemicals. Additionally, it is covered by the CLP regulation, which requires specific hazard communication labels and safety data sheets. In the United States, the FDA and EPA have requirements for the handling and storage of this compound, particularly in relation to its potential health and environmental impacts.

Are there alternatives to 1-Isoindolinone (CAS: 480-91-1) in synthesis?

Yes, there are alternatives to 1-Isoindolinone (CAS: 480-91-1). Commonly used alternatives include 2-Isoindoline-1,3-dione and isoindoline-1,3-dione. These compounds can be used as substitutes in synthesis due to their similar structural properties. Other alternatives may include isomers or analogs of 1-Isoindolinone, which can offer similar functionality in various chemical reactions.

What is the market or research trend for 1-Isoindolinone (CAS: 480-91-1)?

The market for 1-Isoindolinone (CAS: 480-91-1) is growing due to its applications in pharmaceuticals, agrochemicals, and as an intermediate in organic synthesis. Research trends suggest an increasing interest in the use of 1-Isoindolinone for the production of bioactive compounds and as a precursor in the synthesis of complex molecules. Additionally, there is a focus on developing more sustainable and environmentally friendly methods for its production and use.

How should waste containing 1-Isoindolinone (CAS: 480-91-1) be handled?

Waste containing 1-Isoindolinone (CAS: 480-91-1) should be collected in appropriate containers and stored in a well-ventilated area away from ignition sources. Incineration is a common method for disposal, but it should be conducted in an environmentally compliant incinerator. Alternatively, professional waste disposal services can be utilized. Environmental protection measures include ensuring that all waste is treated and disposed of in accordance with local regulations and guidelines to prevent contamination of the environment.