N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine | CAS No. 477600-74-1
N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Basic Information
CAS Number
477600-74-1
Molecular Formula
C13H19N5
Molecular Weight
245.33 g/mol
AD
Basic Physical Properties
Boiling Point
°Cat760mmHg
Density
1.197
Refractive Index
1.636
Synonyms & References
English
- DTXSID70633602
- N-methyl-N-[(3R,4R)-4-methylpiperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- XRIARWQZLGCQDM-KOLCDFICSA-N
- methyl-[(3R,4R)-4-methyl-piperidin-3-yl]-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amine
- N-methyl-N-[(3R,4R)-4-methyl piperidin-3-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- MFCD09878608
- 1206825-36-6
- CS-B0706
- AKOS005258732
- AU-004/43508412
- CS-13040
- SCHEMBL1120755
- N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- AKOS015899957
- AC-24274
- 477600-74-1
- Tofacitinib Impurity 11
- A26940
- 1H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-
- UNII-TD92PJW2H4
- N-methyl-N-(4-methyl-3-piperidinyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- Tofacitinib Impurity M
- J-523688
- methyl-[(3R,4R)-4-methyl-piperidin-3-yl]-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
- TD92PJW2H4
- AMY40127
- N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-, rel-
- N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine
- Methyl-((3R,4R)4-methyl-piperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
- 7H-Pyrrolo(2,3-d)pyrimidin-4-amine, N-methyl-N-((3R,4R)-4-methyl-3-piperidinyl)-
MDL Number
MFCD09878608
FAQ
What are the physical and chemical properties of N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1)?
N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1) is a white to off-white crystalline solid with a molecular weight of approximately 412.44 g/mol. It has a high solubility in organic solvents such as dimethyl sulfoxide (DMSO) and methanol. Chemically, it is relatively stable, but it can react with strong acids or bases under harsh conditions. The compound is typically used in pharmaceuticals and other applications requiring high purity and stability.
How is N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1) typically synthesized?
N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1) is synthesized through multi-step organic synthesis involving the condensation of a pyrrolo[2,3-d]pyrimidine derivative with an amino alcohol derivative. The reaction typically requires a phase transfer catalyst and is performed under mild to moderate conditions. The yield is generally around 70-80%, and the product is purified by recrystallization from an organic solvent.
What industries use N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1)?
N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1) is primarily used in the pharmaceuticals industry for the development of new drugs due to its unique pharmacological properties. It is also used in research and development for other applications such as sensors and semiconductors, although its use in these sectors is less common compared to pharmaceuticals.
What precautions should be taken when handling N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1)?
When handling N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 477600-74-1), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to minimize inhalation risks. If a spill occurs, immediately contain it, clean it up using appropriate absorbent materials, and dispose of the waste according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information and procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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