(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one

Basic Information

$(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one$

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CAS Number

477-47-4

Molecular Formula

C22H22O8

Molecular Weight

414.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

225-227℃

Boiling Point

597.9°C at 760 mmHg

Flash Point

210.2°C

Solubility

H2O: soluble

Refractive Index

1.4480 (estimate)

Specific Rotation

D20 +9.4° (c = 0.7 in chloroform)

SMILES

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COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O

InChI

InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19+,20-/m0/s1

InChIKey

YJGVMLPVUAXIQN-HAEOHBJNSA-N

LogP

2.4092000000000002

Topological Polar Surface Area

92.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 8

Complexity

629

Safety Information

View Safety Information

GHS Hazard Pictograms

H301

H312

H315

H319

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Storage Conditions

2-8℃

Sensitiveness

Light Sensitive

Synonyms & References

English

NSC36407
IGF-1R Inhibitor, PPP
Picropodophyllotoxin, >=96% (HPLC), powder
picro-podophyllin
DTXSID80197245
KBioSS_002116
17434-18-3
KBio2_002116
AXL1717;Picropodophyllin;PPP
s7668
(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
SPECTRUM1504410
BRN 0099161
cyclolignan PPP
NSC799342
Picropodophyllotoxin
CS-1184
SCHEMBL159598
0F35AOI227
BS-16874
(-)PPP
HMS1923O05
(5R,5aR,8aS,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[6,5-f][1,3]benzodioxol-8-one
Picropodophyllin (PPP)
UNII-0F35AOI227
KBioGR_002538
KBio2_007252
CHEMBL283120
GTPL7873
SPBio_000479
AXL1717 (Picropodophyllotoxin)

MDL Number

MFCD01742647

FAQ

What is (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4)?

This compound is a cyclic organic molecule with a specific stereochemistry and functional groups. It contains a tricyclic core with hydroxyl, methoxy, and oxo functionalities. It is characterized by its unique structural features and is used in various applications.

What are the main uses of (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4)?

This compound is primarily used in the pharmaceutical industry as an intermediate in the synthesis of other active pharmaceutical ingredients (APIs). It may also be used in research and development for drug discovery and as a reagent in organic synthesis.

Is (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4) safe?

The safety of this compound depends on the specific use and handling conditions. Proper protective measures should be taken, including the use of gloves, goggles, and appropriate ventilation. It is recommended to follow chemical safety guidelines and consult material safety data sheets (MSDS) for more detailed information.

How should (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4) be stored?

This compound should be stored in a cool, dry place, protected from light and moisture. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should be below 25°C to ensure stability and safety. It is important to follow the manufacturer's storage recommendations and local regulations for handling and disposing of chemicals.

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2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

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Compound Q&A

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Compound Q&A

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Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

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Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

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Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

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Compound Q&A

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Compound Q&A

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Supplier Information

$(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one — Nanjing Chunqiu Bioculture Engineering Co., Ltd.$

Nanjing Chunqiu Bioculture Engineering Co., Ltd.

CAS Number: 477-47-4

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LaiBo （ ShangHai ） ShengHua Technology Co Ltd

CAS Number: 477-47-4

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Chengdu LeMeiTian Medical Technology Co., Ltd.

CAS Number: 477-47-4

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Nantong Zhonghe Chemical New Materials Co., Ltd.

CAS Number: 477-47-4

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$(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one — YunNaXiLiShengWuJiShu Inc$

YunNaXiLiShengWuJiShu Inc

CAS Number: 477-47-4

View Details

$(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one — ShenZhenZhenJiangShengWuJiShu Co Ltd$

ShenZhenZhenJiangShengWuJiShu Co Ltd

CAS Number: 477-47-4

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ChengDouRuiFenSaiDeDan Biotechnology Co Ltd

CAS Number: 477-47-4

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Yiming Biotechnology (Shanghai) Co., Ltd

CAS Number: 477-47-4

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Shanghai Hansi Chemical Co., Ltd.

CAS Number: 477-47-4

View Details

$(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one — HePeng （ ShangHai ） Biotechnology Co Ltd$

HePeng （ ShangHai ） Biotechnology Co Ltd

CAS Number: 477-47-4

View Details

$(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one — Hubei Yangxin Pharmaceutical Technology Co., Ltd.$

(10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one | CAS No. 477-47-4

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Melting Point

Boiling Point

Flash Point

Solubility

Refractive Index

Specific Rotation

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

GHS Hazard Pictograms

Hazard Statement

Hazard Class

Storage Conditions

Sensitiveness

Synonyms & References

English

MDL Number

FAQ

What is (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4)?

What are the main uses of (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4)?

Is (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4) safe?

How should (10R,11S,15R,16R)-16-hydroxy-10-(3,4,5-trimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1,3(7),8-trien-12-one (CAS: 477-47-4) be stored?

Related Compounds

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Supplier Information

Nanjing Chunqiu Bioculture Engineering Co., Ltd.

LaiBo （ ShangHai ） ShengHua Technology Co Ltd

Chengdu LeMeiTian Medical Technology Co., Ltd.

Nantong Zhonghe Chemical New Materials Co., Ltd.

YunNaXiLiShengWuJiShu Inc

ShenZhenZhenJiangShengWuJiShu Co Ltd

ChengDouRuiFenSaiDeDan Biotechnology Co Ltd

Yiming Biotechnology (Shanghai) Co., Ltd

Shanghai Hansi Chemical Co., Ltd.

HePeng （ ShangHai ） Biotechnology Co Ltd

Hubei Yangxin Pharmaceutical Technology Co., Ltd.

Hubei Cuiyuan Biotechnology Co., Ltd.

JiangSuBeiDaYiYao Technology Co Ltd

Hubei Hanwei Chemical Co., Ltd.

Sichuan Jingcuibao Biotechnology Co., Ltd.

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