O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine

Basic Information

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CAS Number

47375-34-8

Molecular Formula

C18H27NO5

Molecular Weight

337.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

115.0 to 119.0 deg-C

Density

1.1160

Water Solubility

Soluble in DMF. Insoluble in water.

Refractive Index

-15.0±1.0°

Specific Rotation

-15 º (c=1% in DMF)

SMILES

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CC(C)(C)OC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OC(C)(C)C

InChI

InChI=1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1

InChIKey

ZEQLLMOXFVKKCN-AWEZNQCLSA-N

LogP

3.3843000000000014

Topological Polar Surface Area

84.86 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

428

Synonyms & References

English

SCHEMBL1311509
MFCD00065598
L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-
HY-W011199
(S)-3-(4-(tert-Butoxy)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid
N-(tert-butyloxycarbonyl)-O-(tert-butyl)-L-tyrosine
BOC-TYR(TBUL)-OH
(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(tert-butoxy)phenyl]propanoic acid
(S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid
AKOS015836421
N-(tert-butoxycarbonyl)-O-(tert-butyl)-L-tyrosine
ZEQLLMOXFVKKCN-AWEZNQCLSA-N
AS-11633
N-alpha-t-Butyloxycarbonyl-O-t-butyl-L-tyrosine
EN300-1589960
N-(tert-butoxycarbonyl)-(O-tert-butyl)-L-tyrosine
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
M03337
AKOS030228093
A827201
Boc-Tyr(tBu)-OH
CS-W011915
Boc-Tyr(tBu)-OH, >=99.0% (sum of enantiomers, TLC)
Boc-O-tert-butyl-L-tyrosine
B3485
N-(tert-Butoxycarbonyl)-O-tert-butyl-L-tyrosine
DTXSID30426916
47375-34-8
N-Boc-O-tert-butyl-L-tyrosine
Boc-L-Tyr(tBu)-OH

MDL Number

MFCD00065598

Customs Code

2924299090

FAQ

What are the physical and chemical properties of O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine (CAS: 47375-34-8)?

O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine is a white crystalline solid with a molecular weight of approximately 332.45 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and acetonitrile. This compound is moderately reactive towards nucleophiles and has good acid-stability. It can be used in various chemical reactions due to its functionality.

How is O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine (CAS: 47375-34-8) typically synthesized?

O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine is typically synthesized via a condensation reaction of 2-methyl-2-propanol with L-tyrosine methyl ester. This process involves the use of a suitable base, such as sodium hydride, and proceeds under mild conditions. The product is isolated via recrystallization from an appropriate solvent.

What industries use O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine (CAS: 47375-34-8)?

O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients. It is also of interest in the polymer industry for the development of functional polymers and in the sensor technology for its potential as a sensing material.

What precautions should be taken when handling O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine (CAS: 47375-34-8)?

When handling O-(2-Methyl-2-propanyl)-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-tyrosine, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store the compound in a fume hood or a well-ventilated area to minimize exposure. In case of a spill, neutralize the acid and disperse the material using an appropriate solvent. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.