Methyl 2-hydroxy-4-methylbenzoate

Basic Information

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CAS Number

4670-56-8

Molecular Formula

C9H10O3

Molecular Weight

166.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

23-28°C

Boiling Point

242°C

Flash Point

28℃

Refractive Index

1.537

SMILES

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Cc1ccc(c(c1)O)C(=O)OC

InChI

InChI=1S/C9H10O3/c1-6-3-4-7(8(10)5-6)9(11)12-2/h3-5,10H,1-2H3

InChIKey

UITFCFWKYAOJEJ-UHFFFAOYSA-N

LogP

1.4872199999999995

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

167

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Methyl 2-hydroxy-4-methylbenzoate
Methyl m-Cresotinate
Methyl 4-methylsalicylate
2-HYDROXY-4-METHYLBENZOIC ACID METHYL ESTER
METHYL 2-HYDROXY-4-METHOXYBENZOATE (METHYL P-METHOXYSALICYLATE)
4-Methylsalicylic Acid Methyl Ester
Methy-4-Methyl Salicylate
Methyl 4-methy
methyl 4-methyl-2-hydroxybenzoate
Methyl m-Cresotate
METHYL-4-MEHTYL SALICYLATE
Methyl-4-Methyl
RARECHEM AL BF 0822
Methyl 2-Hydroxy-4-methylbenzoate

MDL Number

MFCD00020130

Customs Code

29081000

FAQ

What are the physical and chemical properties of Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8)?

Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8) is a crystalline compound with a molecular weight of approximately 194.23 g/mol. It is slightly soluble in water and miscible with organic solvents like ethanol and acetone. Chemically, it is relatively stable but can undergo hydrolysis under acidic conditions. It has a melting point of around 60-62°C and is slightly basic in nature.

How is Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8) typically synthesized?

Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8) is typically synthesized through the esterification of methyl alcohol with 2-hydroxy-4-methylbenzoic acid. Commonly, this process is catalyzed by sulfuric acid under mild heating conditions, yielding high selectivity and good yield. The reaction mixture is then purified by recrystallization to obtain the pure compound.

What industries use Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8)?

Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8) is used in various industries. It is a key intermediate in the synthesis of certain pharmaceuticals, particularly in the production of topical analgesics. It also finds applications in the polymer industry as a plasticizer and in the formulation of sensors and semiconductors due to its optical and electronic properties.

What precautions should be taken when handling Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8)?

When handling Methyl 2-hydroxy-4-methylbenzoate (CAS: 4670-56-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbents and the Material Safety Data Sheet (MSDS) should be consulted for specific safety instructions.