4-(Trifluoromethoxy)aniline

Basic Information

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CAS Number

461-82-5

Molecular Formula

C7H6F3NO

Molecular Weight

177.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

73-75 °C/10 mmHg

Refractive Index

n20/D 1.463(lit.)

SMILES

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C1=CC(=CC=C1N)OC(F)(F)F

InChI

InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2

InChIKey

XUJFOSLZQITUOI-UHFFFAOYSA-N

LogP

2.1673999999999998

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

140

Safety Information

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GHS Hazard Pictograms

H301

H310

H315

H318

H373

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H373 Causes damage to organs through prolonged or repeated exposure
Specific target organ toxicity, repeated exposure

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Sensitive to light

Synonyms & References

English

4-trifluoromethoxy-phenylamine
4-(trifluoro methoxy)aniline
PS-8570
4-trifluoromethoxyphenyl amine
para-(trifluoromethoxy)aniline
XZHAFFSHWJNRFO-UHFFFAOYSA-N
4-(Trifluoromethoxy)aniline, 98%
4-trifluoromethoxy-aniline
DTXSID70196722
HY-W016664
XDDQNRPHVDIKEU-UHFFFAOYSA-N
P-ANISIDINE, .ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-
EINECS 207-317-5
TimTec1_005779
4-trifluoromethoxyphenylamine
4-trifluoromethoxyanilin
MFCD00041314
A937646
AM20040521
4-(triflouromethoxy)aniline
4-(trifluormethoxy)aniline
paratrifluoromethoxyaniline
InChI=1/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2
[4-(Trifluoromethoxy)phenyl]amine
para-trifluoromethoxyaniline
4-(trifluoromethoxy)benzenamine
4-trifluromethoxy aniline
4-(Trifluoromethoxy)aniline
4trifluoromethoxyaniline
P40L42CVF6
EN300-19873

MDL Number

MFCD00041314

Customs Code

2921420090

FAQ

What is 4-(Trifluoromethoxy)aniline (CAS: 461-82-5)?

4-(Trifluoromethoxy)aniline (CAS: 461-82-5) is an organic compound containing an aniline group substituted with a trifluoromethoxy group. It has the chemical formula C7H7F3NO and is known for its aromatic structure and fluorinated side chain. This compound is often used in chemical synthesis due to its reactivity and functional group versatility.

What are the main uses of 4-(Trifluoromethoxy)aniline (CAS: 461-82-5)?

4-(Trifluoromethoxy)aniline (CAS: 461-82-5) is primarily used in pharmaceutical research as a building block for drug development. It also finds applications in organic synthesis, material science, and as an intermediate in the production of various chemicals. Its unique properties make it valuable in the development of agrochemicals and specialty polymers.

Is 4-(Trifluoromethoxy)aniline (CAS: 461-82-5) safe?

4-(Trifluoromethoxy)aniline (CAS: 461-82-5) is considered toxic and should be handled with appropriate safety measures. It is classified as a hazardous chemical, requiring protective equipment such as gloves and goggles. Safety standards emphasize proper ventilation and adherence to OSHA and EPA guidelines to minimize exposure risks.

How should 4-(Trifluoromethoxy)aniline (CAS: 461-82-5) be stored?

4-(Trifluoromethoxy)aniline (CAS: 461-82-5) should be stored in a cool, dry, and well-ventilated area, away from light. It is typically kept in a sealed container made of glass or HDPE to prevent contamination. Storage conditions should maintain a temperature below 25°C and avoid exposure to moisture or air to ensure stability.