1,1,1-Trifluoro-3-iodopropane

Basic Information

View in Editor

CAS Number

460-37-7

Molecular Formula

C3H4F3I

Molecular Weight

223.96 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

90°C

Refractive Index

n20/D 1.42(lit.)

SMILES

View in Editor

C(CI)C(F)(F)F

InChI

InChI=1S/C3H4F3I/c4-3(5,6)1-2-7/h1-2H2

InChIKey

ULIYQAUQKZDZOX-UHFFFAOYSA-N

LogP

2.3738

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

48.6

Safety Information

View Safety Information

Hazard Statement

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Light Sensitive

Synonyms & References

English

DTXSID10963475
(3,3,3-trifluoro)-1-iodopropane
1,1,1-tris(fluoranyl)-3-iodanyl-propane
1,1,1-Trifluoro-3-iodopropane, 97%
460-37-7
CS-W002174
A826971
MFCD00038531
BCP08523
1,1,1-Trifluoro-3-iodopropane
AKOS005063359
FT-0615882
3-iodo-1,1,1-trifluoropropane
T2588
trifluoroiodopropane
EN300-156159
3,3,3-trifluoropropyl iodid
1-Iodo-3,3,3-trifluoropropane
1-Iodo-3,3,3-trifluoropropane over Cu
FD2005
3,3,3-trifluoro-1-iodopropane
Propane, 1,1,1-trifluoro-3-iodo-
SY030988
3,3,3-Trifluoropropyliodide
J-504802
SCHEMBL9984
1-iodo-3,3,3-trifluoro-propane
71215-70-8
AMY6816
1,1,1-trifluoro-3-iodo-propane
AS-10244

MDL Number

MFCD00038531

Customs Code

2903799090

FAQ

What are the physical and chemical properties of 1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7)?

1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7) is a colorless, crystalline solid with a high molecular weight of approximately 286.97 g/mol. It has a low solubility in water but is more soluble in organic solvents. The compound is relatively unreactive under normal conditions but can undergo nucleophilic substitution reactions. It is highly flammable and can react exothermically with strong oxidizers.

How is 1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7) typically synthesized?

1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7) can be synthesized via the reaction of 1,1,1-trifluoro-2-propanol with iodine in the presence of a Lewis acid catalyst, such as aluminum chloride. This method provides good yields and selectivity. Alternately, it can be prepared by the reaction of 1,1,1-trifluoro-2-propanol with sodium iodide in anhydrous conditions.

What industries use 1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7)?

1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7) is used in the pharmaceutical industry for the synthesis of drugs, particularly those requiring iodine functionality. It is also utilized in the polymer industry for the modification of polymers and in the electronics industry for the fabrication of semiconductor materials.

What precautions should be taken when handling 1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7). It should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using absorbent materials and the area should be flushed with water. In case of accidental ingestion or skin contact, seek medical attention immediately. A Material Safety Data Sheet (MSDS) should always be consulted for detailed safety information.