Compound Q&A

How is 1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7) typically synthesized?

Answer

1,1,1-Trifluoro-3-iodopropane
1,1,1-Trifluoro-3-iodopropane (CAS: 460-37-7) can be synthesized via the reaction of 1,1,1-trifluoro-2-propanol with iodine in the presence of a Lewis acid catalyst, such as aluminum chloride. This method provides good yields and selectivity. Alternately, it can be prepared by the reaction of 1,1,1-trifluoro-2-propanol with sodium iodide in anhydrous conditions.

About

CAS No 460-37-7
English Name 1,1,1-Trifluoro-3-iodopropane
Molecular Formula C3H4F3I
Molecular Weight 223.96 g/mol
SMILES C(CI)C(F)(F)F
InChIKey ULIYQAUQKZDZOX-UHFFFAOYSA-N
Last Updated: 2025-09-10 15:15

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