1-fluoro-4-methoxybenzene

Basic Information

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CAS Number

459-60-9

Molecular Formula

C7H7FO

Molecular Weight

126.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

−45 °C

Boiling Point

157°C

Water Solubility

Not miscible or difficult to mix in water.

Refractive Index

n20/D 1.488(lit.)

SMILES

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COC1=CC=C(C=C1)F

InChI

InChI=1S/C7H7FO/c1-9-7-4-2-6(8)3-5-7/h2-5H,1H3

InChIKey

VIPWUFMFHBIKQI-UHFFFAOYSA-N

LogP

1.8343

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

Safety Information

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GHS Hazard Pictograms

H226

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Synonyms & References

English

NSC-4672
4-METHOXYFLUOROBENZENE
MFCD00000348
F0231
4-Fluoro-1-methoxybenzene
CK1195
p-Fluoromethoxybenzene
FT-0618503
DTXSID3060033
Benzene, 1-fluoro-4-methoxy-
F6A62M57LM
1219802-94-4
Anisole, p-fluoro-
A826944
p-Fluorophenyl methyl ether
4-fluoromethoxybenzene
p-Fluoroanisole
EINECS 207-295-7
1-FLUORO-4-METHOXYBENZENE
CS-W016565
4-Fluoroanisole
Q63395414
SCHEMBL8298
4-Fluoroanisole--d4
NSC4672
SCHEMBL12015227
AM20040516
NSC 4672
p-Methoxyfluorobenzene
EN300-16113
4-Fluoro-anisole

MDL Number

MFCD00000348

Customs Code

2909309090

FAQ

What is 1-fluoro-4-methoxybenzene (CAS: 459-60-9)?

1-Fluoro-4-methoxybenzene, with the CAS number 459-60-9, is an aromatic compound containing a fluorine atom and a methoxy group attached to a benzene ring. Its chemical formula is C7H7FO2. It is a colorless liquid with a mild aromatic odor and exhibits moderate solubility in organic solvents. This compound is known for its stability under normal conditions and is commonly used as an intermediate in organic synthesis.

What are the main uses of 1-fluoro-4-methoxybenzene (CAS: 459-60-9)?

1-Fluoro-4-methoxybenzene is primarily used in pharmaceutical research as a building block for drug development. It also finds applications in the synthesis of agrochemicals, dyes, and electronic materials. Due to its functional groups, it is valuable in creating derivatives for various industrial and research purposes, including organic chemistry and chemical manufacturing.

Is 1-fluoro-4-methoxybenzene (CAS: 459-60-9) safe?

1-Fluoro-4-methoxybenzene is generally considered safe when handled properly, but it should be treated with caution. It has low acute toxicity but may cause irritation to the skin, eyes, and respiratory system. Safety measures include using appropriate personal protective equipment (PPE), ensuring good ventilation, and following standard chemical safety protocols to minimize exposure and risk.

How should 1-fluoro-4-methoxybenzene (CAS: 459-60-9) be stored?

1-Fluoro-4-methoxybenzene should be stored in a cool, dry, and well-ventilated place, away from light and heat sources. It is best kept in a sealed, airtight container made of inert material such as glass or stainless steel. Storage conditions should maintain a temperature below 25°C and humidity levels below 60% to ensure stability and prevent degradation.