(1R)-1-(4-Bromophenyl)ethanamine

Basic Information

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CAS Number

45791-36-4

Molecular Formula

C8H10BrN

Molecular Weight

200.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

-25 °C(NEAT)

Boiling Point

140-145 ºC (30 mmHg)

Flash Point

>110℃(230℉)(lit.)

Refractive Index

n20/D 1.566

Specific Rotation

20.5 º (c=3% in MeOH)

SMILES

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CC(C1=CC=C(C=C1)Br)N

InChI

InChI=1S/C8H10BrN/c1-6(10)7-2-4-8(9)5-3-7/h2-6H,10H2,1H3/t6-/m1/s1

InChIKey

SOZMSEPDYJGBEK-ZCFIWIBFSA-N

LogP

2.4688

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

97.4

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

NS00031558
SCHEMBL352653
EN300-34285
45791-36-4
SOZMSEPDYJGBEK-ZCFIWIBFSA-N
(1R)-1-(4-bromophenyl)ethanamine
A7187
AC-9523
(1R)-1-(4-bromophenyl)ethan-1-amine
(R)-(+)-4-Bromo-alpha-methylbenzylamine
(R)-1-(4-bromophenyl)ethanamine
(R)-(+)-1-(4-Bromophenyl)ethylamine, ChiPros?
(R)-4-Bromo-alpha-methylbenzylamine
(R)-1-(4-Bromophenyl)ethylamine
(R)-(+)-4-bromo A-methylbenzylamine
AKOS015835626
DTXSID10196620
AS-18370
(R)-1-(4-bromo-phenyl)-ethylamine
CS-B0174
(R)-1-(4-bromophenyl)ethan amine
(R)-(+)-1-(4-Bromophenyl)ethylamine
(R)-(+)-1-(4-Bromophenyl)ethylamine, >=96.0% (sum of enantiomers, GC)
(R)-(+)-1-(4- Bromophenyl)ethylamine
(R)-1-(4-Bromophenyl)-ethylamine
B3672
(R)-(+)-1-(p-bromophenyl)ethylamine
(R)-(+)-1-(4-Bromophenyl)ethylamine, ChiPros(R), produced by BASF, 99%
AKOS010367581
MFCD00066025
(R)-1-(4-bromophenyl)ethyl amine

MDL Number

MFCD00066025

Customs Code

2921499090

FAQ

What are the physical and chemical properties of (1R)-1-(4-Bromophenyl)ethanamine (CAS: 45791-36-4)?

(1R)-1-(4-Bromophenyl)ethanamine is a white crystalline solid with a molecular weight of approximately 218.04 g/mol. It has a slight smell and is slightly soluble in water. It is reactive towards bases due to the presence of the primary amine group. This compound is less soluble in polar solvents and more soluble in non-polar solvents. It is an important building block in organic synthesis and pharmaceuticals.

How is (1R)-1-(4-Bromophenyl)ethanamine (CAS: 45791-36-4) typically synthesized?

(1R)-1-(4-Bromophenyl)ethanamine is typically synthesized through the reduction of 4-bromophenacyl bromide with a suitable reducing agent such as sodium borohydride. The reaction is carried out under anhydrous conditions and is highly selective, providing a yield of up to 90%. This method allows for the production of the desired enantiomer with good enantioselectivity.

What industries use (1R)-1-(4-Bromophenyl)ethanamine (CAS: 45791-36-4)?

(1R)-1-(4-Bromophenyl)ethanamine is used in the pharmaceutical industry for the synthesis of drugs and intermediates. It is also utilized in the development of organic semiconductors, particularly in the field of organic electronics. Additionally, this compound has applications in the production of chemical sensors and as a precursor in polymer synthesis.

What precautions should be taken when handling (1R)-1-(4-Bromophenyl)ethanamine (CAS: 45791-36-4)?

When handling (1R)-1-(4-Bromophenyl)ethanamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation of vapors. Spills should be immediately neutralized with an appropriate base and cleaned up with absorbent material. Always refer to the Safety Data Sheet (SDS) for specific handling and storage instructions.