Disodium 5'-O-phosphonatoadenosine

Basic Information

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CAS Number

4578-31-8

Molecular Formula

C10H12N5Na2O7P

Molecular Weight

391.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

232-235°C

Boiling Point

No data available

Density

1.5250

Water Solubility

Soluble in water, dimethyl sulfoxide and methanol.

Flash Point

No data available

Solubility

H2O: soluble

Vapor Pressure

No data available

Specific Rotation

-43 ±2° (c=1%, in 0.5 M Na2HPO4)

SMILES

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O=P([O-])([O-])OC[C@H]1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O.[Na+].[Na+]

InChI

InChI=1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1

InChIKey

QGXLVXZRPRRCRP-IDIVVRGQSA-L

LogP

-0.40540

Complexity

469

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

对空气及湿度敏感

Synonyms & References

English

5'-ADENYLIC ACID SODIUM SALT
5-ADENYLIC ACID, SODIUM SALT
5'-AMP 2NA
5'-AMP DISODIUM SALT
5'-AMP-NA2
5'-AMP SODIUM SALT
A-5'-P SODIUM SALT
ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT
ADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
ADENOSINE-5'-MONOPHOSPHORIC ACID, DISODIUM
ADENOSINE 5'-MONOPHOSPHORIC ACID DISODIUM SALT
ADENOSINE 5'-MONOPHOSPHORIC ACID SODIUM SALT
ADENOSINE-5'-PHOSPHATE, DISODIUM SALT
ADENOSINE-5'-PHOSPHATE NA2-SALT
ADENOSINE MONOPHOSPHATE DINA SALT
AMP
AMP, 2NA
AMP DISODIUM SALT
AMP, NA2
AMP SODIUM SALT
Adenosine 5'-monophosphate disodium salt
5'-Adenylic acid disodium salt
Adenosine 5’-Monophosphate Disodium Salt
Disodium adenosine 5'-phosphate
5′-AMP-Na2
DisodiuM Adenosine 5-Phosphate
5'-AMP，2Na
Sodium ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate
Disodium AMP
Disodium 5'-AMP
Adenosine Phosphate Disodium

MDL Number

MFCD00065023

FAQ

What is Disodium 5'-O-phosphonatoadenosine (CAS: 4578-31-8)?

Disodium 5'-O-phosphonatoadenosine is a chemical compound with the CAS number 4578-31-8. It is a sodium salt of adenosine with a phosphonate group at the 5' position. This compound is typically a white solid and is known for its solubility in water. It plays a role in biochemical studies and is often used as an inhibitor in enzymatic reactions involving adenosine monophosphate (AMP).

What are the main uses of Disodium 5'-O-phosphonateadenosine (CAS: 4578-31-8)?

Disodium 5'-O-phosphonateadenosine is primarily used in pharmaceutical research as an inhibitor of adenosine deaminase, which is relevant in the development of antiviral and anticancer drugs. It also finds application in biochemical studies, nucleotide metabolism research, and as a component in certain buffer solutions. Additionally, it may be used in industrial and analytical settings for specific chemical processes.

Is Disodium 5'-O-phosphonateadenosine (CAS: 4578-31-8) safe?

Disodium 5'-O-phosphonateadenosine is generally considered safe when handled properly in controlled environments. However, as with many chemical compounds, it should be handled with care, avoiding prolonged skin contact and inhalation. Safety data sheets (SDS) recommend using appropriate personal protective equipment (PPE) such as gloves and goggles. It is not classified as toxic under standard conditions but should be treated as a bioactive compound requiring caution in laboratory settings.

How should Disodium 5'-O-phosphonateadenosine (CAS: 4578-31-8) be stored?

Disodium 5'-O-phosphonateadenosine should be stored in a dry, cool place away from direct sunlight. It is typically kept in a sealed container to prevent moisture absorption. Storage conditions should maintain a temperature between 2°C to 8°C and a relative humidity below 60%. Proper storage helps ensure the compound's stability and prolongs its shelf life for research and industrial use.