1,3-Oxazol-2-amine

Basic Information

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CAS Number

4570-45-0

Molecular Formula

C3H4N2O

Molecular Weight

84.08 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

93.0 to 97.0 deg-C

Boiling Point

186.6°C at 760 mmHg

Flash Point

66.702℃

SMILES

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Nc1ncco1

InChI

InChI=1S/C3H4N2O/c4-3-5-1-2-6-3/h1-2H,(H2,4,5)

InChIKey

ACTKAGSPIFDCMF-UHFFFAOYSA-N

LogP

0.25680000000000003

Topological Polar Surface Area

52.05 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

48.1

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Oxazol-2-amine
2-Aminooxazole
1,3-Oxazol-2-amine
2-AMINO-1,3-OXAZOLE
Oxazole-2-amine
2-AMino-Oxazole
2-Oxazolamine
2-Oxazolamine Oxazole-2-ylamine
Oxazol-2-ylamine
Oxazole-2-ylamine
Oxazole,2-amino- (6CI,7CI,8CI)
2-Aminoxazole
1,3-oxazole-2-ylamine
imino oxazole
oxazolyl amine
oxazole 2-amine
2-amino oxazole
1,3-oxazole-2-amine
1,3-oxazol-2-ylamine
2-amino-(I,3)-oxazole
1,3-Oxazol-2-amine #
KSC235K8L
Oxazol-2-amineoxazol-2-amine
AMOT0093
BCP23469
STK695461
SBB019333
1,3-oxazol-2-amine

MDL Number

MFCD07364485

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 1,3-Oxazol-2-amine (CAS: 4570-45-0)?

1,3-Oxazol-2-amine is a colorless to light yellow liquid at room temperature. Its molecular weight is approximately 97.11 g/mol. This compound is slightly soluble in water but has good solubility in organic solvents. It reacts readily with acids to form amides and with bases to form the corresponding salts. 1,3-Oxazol-2-amine is stable under normal conditions but can be hydrolyzed under basic conditions.

How is 1,3-Oxazol-2-amine (CAS: 4570-45-0) typically synthesized?

1,3-Oxazol-2-amine can be synthesized via the reaction of 1,3-diazol-2-one with amines in the presence of sodium hydroxide. Another method involves the reduction of 1,3-diazol-2-one using sodium borohydride in an aqueous medium. The yield and selectivity are influenced by the choice of reactants and reaction conditions.

What industries use 1,3-Oxazol-2-amine (CAS: 4570-45-0)?

1,3-Oxazol-2-amine finds applications in the pharmaceutical industry for the synthesis of bioactive compounds, in the polymer industry as a crosslinking agent, in sensor technology for detecting specific chemicals, and in the semiconductor industry as a precursor for organic semiconductors.

What precautions should be taken when handling 1,3-Oxazol-2-amine (CAS: 4570-45-0)?

When handling 1,3-Oxazol-2-amine, it is recommended to use personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. In case of spillage, the area should be cleaned up immediately using appropriate absorbents, and the substance should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.