1,1,3,3-Tetrabutylurea | CAS No. 4559-86-8

Q: What are the physical and chemical properties of 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8)?

1,1,3,3-Tetrabutylurea (CAS: 4559-86-8) is a white crystalline solid with a molecular weight of 238.36 g/mol. It has poor solubility in water but is soluble in organic solvents. Chemically, it is moderately reactive, particularly under basic conditions, making it useful in a variety of synthesis applications.

Q: How is 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8) typically synthesized?

1,1,3,3-Tetrabutylurea is typically synthesized by the reaction of 1,3-dibutylurea with butanol in the presence of a strong acid catalyst, such as hydrochloric acid. The reaction is carried out under mild conditions, and the yield can be up to 85%. The product is then purified by recrystallization.

Q: What industries use 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8)?

1,1,3,3-Tetrabutylurea is used in various industries, including pharmaceuticals, where it serves as a raw material for drug synthesis, and in polymer production for its ability to enhance properties such as viscosity and solubility. It is also used in the production of sensors and semiconductors due to its reactivity and stability.

Q: What precautions should be taken when handling 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8)?

When handling 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The substance should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, it should be cleaned up using appropriate absorbents, and the area should be thoroughly cleaned. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.

1,1,3,3-Tetrabutylurea

Basic Information

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CAS Number

4559-86-8

Molecular Formula

C17H36N2O

Molecular Weight

284.49 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

<-50°C

Boiling Point

163°C/12mmHg

Flash Point

93 °C

Refractive Index

1.4520-1.4560

SMILES

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CCCCN(CCCC)C(=O)N(CCCC)CCCC

InChI

InChI=1S/C17H36N2O/c1-5-9-13-18(14-10-6-2)17(20)19(15-11-7-3)16-12-8-4/h5-16H2,1-4H3

InChIKey

SNDGLCYYBKJSOT-UHFFFAOYSA-N

LogP

4.910800000000005

Topological Polar Surface Area

23.550000000000004 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

193

Safety Information

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GHS Hazard Pictograms

H227

Hazard Statement

H227 Combustible liquid
Flammable liquids

Synonyms & References

English

1,1,3,3-Tetrabutylurea
N,N,N',N'-TETRABUTYLUREA
N,N,N',N'-TETRA-N-BUTYLUREA
TETRABUTYL UREA
TETRA-N-BUTYLUREA
1,1,3,3-tetrabutyl-ure
tetrabutyl-ure
Tetra Butyl Ureas ( TBU )
Urea, tetrabutyl-
Tetrabutylharnstoff
Tetrabutyl-urea
Tetrabutylurea
Urea, 1,1,3,3-tetrabutyl-
Urea, N,N,N',N'-tetrabutyl-
SNDGLCYYBKJSOT-UHFFFAOYSA-N
N,N,N,N-TETRA-N-BUTYLUREA
736CY99V47
tetra-n-Butyl urea
TBU (Tetrabutylurea)
DSSTox_CID_23902
DSSTox_RID_80085
1,1,3,3-tetrabutyl-urea
DSSTox_GSID_43902
Urea,N,N,N',N'-tetra

MDL Number

MFCD00042901

Customs Code

2924199090

FAQ

What are the physical and chemical properties of 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8)?

1,1,3,3-Tetrabutylurea (CAS: 4559-86-8) is a white crystalline solid with a molecular weight of 238.36 g/mol. It has poor solubility in water but is soluble in organic solvents. Chemically, it is moderately reactive, particularly under basic conditions, making it useful in a variety of synthesis applications.

How is 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8) typically synthesized?

1,1,3,3-Tetrabutylurea is typically synthesized by the reaction of 1,3-dibutylurea with butanol in the presence of a strong acid catalyst, such as hydrochloric acid. The reaction is carried out under mild conditions, and the yield can be up to 85%. The product is then purified by recrystallization.

What industries use 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8)?

1,1,3,3-Tetrabutylurea is used in various industries, including pharmaceuticals, where it serves as a raw material for drug synthesis, and in polymer production for its ability to enhance properties such as viscosity and solubility. It is also used in the production of sensors and semiconductors due to its reactivity and stability.

What precautions should be taken when handling 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8)?

When handling 1,1,3,3-Tetrabutylurea (CAS: 4559-86-8), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The substance should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, it should be cleaned up using appropriate absorbents, and the area should be thoroughly cleaned. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.