Diphenylphosphine oxide

Basic Information

View in Editor

CAS Number

4559-70-0

Molecular Formula

C12H11OP

Molecular Weight

202.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

56-57 °C

Boiling Point

105°C/0.4mmHg

Water Solubility

Slightly soluble in water.

Flash Point

152.9 °C

Refractive Index

1.608-1.61

SMILES

View in Editor

C1=CC=C(C=C1)[P+](=O)C2=CC=CC=C2

InChI

InChI=1S/C12H11OP/c13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,14H

InChIKey

ASUOLLHGALPRFK-UHFFFAOYSA-N

LogP

2.1971

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

171

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Moisture Sensitive

Synonyms & References

English

Diphenylphosphine oxide
AKOS015918462
di-phenylphosphine oxide
EN300-139799
(PHENYLPHOSPHOROSO)BENZENE
AURORA KA-1314
CHEBI:191101
C12H11OP
XXW49HG6X3
SCHEMBL1667
oxo(diphenyl)phosphanium
SY049043
NSC77604
Q-201010
Phosphine oxide, diphenyl-
HMS1542H05
CS-W007660
TimTec1_002975
AKOS005442498
D2826
F14956
DIPHENYLPHOSPHINEOXIDE
FT-0654486
diphenyl phosphine oxide
BRD-K25200832-001-01-4
phenyl-phosphonoyl-benzene
NS00014204
DPPO
4559-70-0
Diphenylphosphine oxide, 97%
DTXSID60422562

MDL Number

MFCD00002079

Customs Code

2902909090

FAQ

What is Diphenylphosphine oxide (CAS: 4559-70-0)?

Diphenylphosphine oxide (CAS: 4559-70-0) is an organic compound with the chemical formula C12H10PO. It is a white solid with a characteristic phosphorus-containing odor, known for its hygroscopic nature and use as a versatile reagent in chemical synthesis. The compound exhibits moderate solubility in organic solvents and is commonly employed in pharmaceutical and industrial applications due to its reactivity and stability under controlled conditions.

What are the main uses of Diphenylphosphine oxide (CAS: 4559-70-0)?

Diphenylphosphine oxide (CAS: 4559-70-0) is widely used in pharmaceuticals as an intermediate for drug development, in organic synthesis for forming phosphorus-containing compounds, and in industrial processes such as flame retardants and polymer production. It also serves as a catalyst in various chemical reactions and is a key component in research involving materials science and biochemical applications.

Is Diphenylphosphine oxide (CAS: 4559-70-0) safe?

Diphenylphosphine oxide (CAS: 4559-70-0) requires careful handling due to its potential chemical hazards. While it is generally considered stable, it may cause irritation to the skin, eyes, or respiratory system. Safety standards recommend using appropriate PPE, ensuring proper ventilation, and avoiding contact with moisture. Always follow OSHA guidelines and manufacturer instructions for safe use.

How should Diphenylphosphine oxide (CAS: 4559-70-0) be stored?

Diphenylphosphine oxide (CAS: 4559-70-0) should be stored in a cool, dry, and dark location, ideally at 0–8°C. Keep it in airtight, moisture-proof containers made of glass or plastic to maintain stability. Avoid exposure to incompatible substances and ensure proper labeling to prevent accidental contamination or misuse.