4-(Trifluoromethyl)benzaldehyde

Basic Information

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CAS Number

455-19-6

Molecular Formula

C8H5F3O

Molecular Weight

174.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

1-2°C

Boiling Point

64°C/12mmHg

Water Solubility

Soluble in water. 1.5 g/L at 20°C

Solubility

1.5g/l

Refractive Index

n20/D 1.463(lit.)

SMILES

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C1=CC(=CC=C1C=O)C(F)(F)F

InChI

InChI=1S/C8H5F3O/c9-8(10,11)7-3-1-6(5-12)2-4-7/h1-5H

InChIKey

BEOBZEOPTQQELP-UHFFFAOYSA-N

LogP

2.517900000000001

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

156

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class Comb liq Class Comb liq

Sensitiveness

Air Sensitive

Synonyms & References

English

NS00043594
4-(trifluormethyl)-benzaldehyde
4-Trifluoromethylbenzaldehyde
4-(trifluoromethyl) benzaldehyde
trifluoro-p-tolualdehyde
FT-0616908
p-(Trifluoromethyl)benzaldehyde
p-Trifluoromethylbenzaldehyde
a,a,a-tri-fluoro-p-tolualdehyde
SY003301
J-513913
A7169
4-(Trifluoromethyl)benzaldehyde, 98%
P17751
DTXSID0060016
4-trifluromethylbenzaldehyde
A,A,A-TRIFLUORO-P-TOLUALDEHYDE
AKOS000118848
455-19-6
4-trifluoromethyl benzaldehyde
.alpha.,.alpha.,.alpha.-Trifluoro-p-tolualdehyde
4-trifluormethylbenzaldehyde
EN300-19394
4-(Trifluoromethyl)benzaldehyde, purum, >=97.0% (GC)
alpha,alpha,alpha-trifluro-p-tolualdehyde
p-CF3C6H4CHO
CHEBI:156309
4-trifluoromethyl-benzaldehyde
Para-(trifluoromethyl)benzaldehyde
4-(trifluoromethyl)-benzaldehyde
4-Trifluoromethylbenzaldehyde (alpha,alpha,alpha-Trifluoro-p-tolualdehyde)

MDL Number

MFCD00006952

Customs Code

2918300090

FAQ

What is 4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6)?

4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6) is an aromatic aldehyde with a trifluoromethyl group attached to the benzene ring. Its chemical formula is C8H6F3O, and it appears as a colorless liquid with a faint aromatic odor. The compound is known for its stability and reactivity in organic synthesis, making it a key intermediate in fluorinated compound development. It exhibits low solubility in water but is soluble in organic solvents like ethanol and acetone.

What are the main uses of 4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6)?

4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6) is widely used in pharmaceuticals as a building block for drugs with enhanced metabolic stability. It serves as a precursor in the synthesis of agrochemicals, dyes, and materials science applications. The compound's fluorinated structure is valuable in research for developing functionalized molecules, while its industrial applications include the production of specialty chemicals and intermediates for various sectors. Its unique properties make it a critical component in synthetic chemistry.

Is 4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6) safe?

4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6) is generally considered low toxicity when handled properly, but it requires standard safety precautions. Prolonged skin or eye contact may cause irritation, so personal protective equipment (PPE) like gloves, goggles, and lab coats is recommended. The compound should be used in well-ventilated areas to avoid inhalation risks. Safety data sheets (SDS) advise avoiding exposure to heat or moisture. It complies with regulatory guidelines for chemical handling but necessitates careful storage and use to ensure safety.

How should 4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6) be stored?

4-(Trifluoromethyl)benzaldehyde (CAS: 455-19-6) should be stored in a sealed, airtight container in a cool, dry place away from light. It is stable under normal conditions but may degrade if exposed to moisture or high temperatures. Storage in a ventilated chemical cabinet is recommended to maintain safety and prevent contamination. Always keep the container closed when not in use to ensure long-term stability and minimize risks associated with handling. Maintain humidity levels below 60% for optimal preservation.