3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

Basic Information

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CAS Number

452972-13-3

Molecular Formula

C11H15BBrNO2

Molecular Weight

283.96 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

71-75 °C

Boiling Point

341.4℃/760mmHg

SMILES

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B1(OC(C(O1)(C)C)(C)C)C2=CC(=CN=C2)Br

InChI

InChI=1S/C11H15BBrNO2/c1-10(2)11(3,4)16-12(15-10)8-5-9(13)7-14-6-8/h5-7H,1-4H3

InChIKey

JSUVNRWVYRZAOS-UHFFFAOYSA-N

LogP

2.1433

Topological Polar Surface Area

31.35 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

257

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3-Bromopyridine-5-boronic acid pinacol ester
5-Bromopyridine-3-boronic acid, pinacol ester
EN300-1894073
JSUVNRWVYRZAOS-UHFFFAOYSA-N
3-Bromo-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine
3-bromo-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
SCHEMBL925705
CTA97213
CS-0041166
5-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;5-Bromo-3-pyridineboronic acid pinacol ester
5-Bromo-3-pyridineboronic acid pinacol ester, 90%
5-Bromo-3-pyridineboronic acid pinacol ester
BCP21914
DTXSID80476865
452972-13-3
5-Bromopyridine-3-boronic acid,pinacol ester
DIETHYL1-DECYLPHOSPHONATE
Z2044798540
A25342
H11400
AKOS015834940
DS-13750
3-Bromo-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine
FT-0644700
AB29855
3-Bromopyridine-5-boronic acid pinacol ester
AM20051192
3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Pyridine,3-bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
3-bromopyridin-5-ylboronic acid

MDL Number

MFCD06798248

Customs Code

2934999090

FAQ

What is 3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3)?

3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3) is a pyridine derivative with a bromine substituent and a tetramethyl-1,3,2-dioxaborole substituent. It is a colorless to white solid with limited solubility in common organic solvents. This compound is used in organic synthesis, particularly in the field of medicinal chemistry for its boron-containing functionality.

What are the main uses of 3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3)?

3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3) is primarily used in the synthesis of pharmaceuticals and biologically active compounds. Its boron-containing functionality facilitates reactions in organic chemistry, making it a valuable reagent in the development of new drugs and materials.

Is 3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3) safe?

3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3) is generally considered safe when handled with proper precautionary measures. However, it is important to avoid contact with skin and eyes, and to ensure proper ventilation during use. Protective gloves and goggles should be worn to prevent direct exposure.

How should 3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3) be stored?

3-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 452972-13-3) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture and air exposure. Refrigeration is not required but can be beneficial to maintain its stability.