2,3-Pyridinediamine

Basic Information

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CAS Number

452-58-4

Molecular Formula

C5H7N3

Molecular Weight

109.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

110-115 °C

Boiling Point

311.3°C at 760 mmHg

Water Solubility

100 g/L (20 ºC)

Flash Point

205 ºC

Solubility

H2O: soluble50mg/mL, opaque (brown to very dark brown)

Refractive Index

1.5340 (estimate)

SMILES

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C1=CC(=C(N=C1)N)N

InChI

InChI=1S/C5H7N3/c6-4-2-1-3-8-5(4)7/h1-3H,6H2,(H2,7,8)

InChIKey

ZZYXNRREDYWPLN-UHFFFAOYSA-N

LogP

0.2460000000000001

Topological Polar Surface Area

64.92999999999999 Å²

Hydrogen Bond Donor/Acceptor

4 / 3

Complexity

74.1

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Air Sensitive

Synonyms & References

English

2,3-Diaminopyridine
pyridine-2,3-diamine
2,3-diamino pyridine
76X
DTXCID9030676
DIAMINOPYRIDINE
'pyridine-2,3-diamine'
AI3-52327
AC-907/25014077
2,3-Diaminopyridine, Vetec(TM) reagent grade, 94%
Tox21_303818
NCGC00357096-01
BG-0085
D0117
2,3 diamino pyridine
Z385438806
Benzenepropanoic acid, 4-chloro-.beta.-oxo-, ethyl ester
2,3-diamino-pyridine
CBX394737H
NSC-45406
SB75564
MFCD00006319
AM20070113
Pyridine-2,3-diyldiamine
'2,3-Diaminopyridine'
AKOS005135856
BRN 0109869
STR01839
W-106156
2,3-Pyridinediamine
AC-3570

MDL Number

MFCD00006319

Customs Code

2933399090

FAQ

What is 2,3-Pyridinediamine (CAS: 452-58-4)?

2,3-Pyridinediamine (CAS: 452-58-4) is a chemical compound with the formula C5H7N3. It is a colorless solid characterized by its two amino groups attached to the 2 and 3 positions of the pyridine ring, making it a key intermediate in organic synthesis. The compound is known for its hygroscopic nature and basic properties, often used in pharmaceutical and industrial applications due to its reactivity and structural versatility.

What are the main uses of 2,3-Pyridinediamine (CAS: 452-58-4)?

2,3-Pyridinediamine (CAS: 452-58-4) is primarily used in pharmaceuticals as a building block for drugs targeting fungal and bacterial infections. It also serves in industrial chemistry for producing dyes, pesticides, and other nitrogen-containing compounds. In research, it functions as a versatile reagent for synthesizing complex molecules. Its applications are broad, leveraging its chemical structure and reactivity in various sectors.

Is 2,3-Pyridinediamine (CAS: 452-58-4) safe?

2,3-Pyridinediamine (CAS: 452-58-4) requires careful handling due to its potential toxicity. It may cause irritation to the skin, eyes, and respiratory system, and is classified as a hazardous substance under safety standards like REACH. Precautions include using personal protective equipment (PPE), ensuring proper ventilation, and avoiding direct contact. Safety protocols are essential to mitigate risks during storage, transportation, and use.

How should 2,3-Pyridinediamine (CAS: 452-58-4) be stored?

2,3-Pyridinediamine (CAS: 452-58-4) should be stored in a cool, dry, and temperature-controlled environment (ideally below 25°C). It is sensitive to moisture and air, so it must be kept in airtight, moisture-resistant containers. Storage away from light is recommended to maintain stability. Always follow safety guidelines to prevent degradation or hazardous reactions.