6-Ethoxy-1,3-benzothiazole-2-sulfonamide

Basic Information

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CAS Number

452-35-7

Molecular Formula

C9H10N2O3S2

Molecular Weight

258.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

190-193 °C

Boiling Point

464.9°Cat760mmHg

Flash Point

235°C

Refractive Index

1.6800 (estimate)

SMILES

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CCOC1=CC2=C(C=C1)N=C(S2)S(=O)(=O)N

InChI

InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)

InChIKey

OUZWUKMCLIBBOG-UHFFFAOYSA-N

LogP

1.3424000000000003

Topological Polar Surface Area

82.28 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

341

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

NSC10679
SW220095-1
CHEMBL18
HMS3746M15
6-Ethoxy-1,3-benzothiazole-2-sulfonamide #
NS00031505
HMS2094M03
Ethoxyzolamide
6-Ethoxybenzothiazole-2-sulfonamide
NCGC00186657-01
2-Benzothiazolesulfonamide, 6-ethoxy-
6-Ethoxy-2-benzothiazolesulfonamide, 97%
HMS2093J03
VS-0126
Q265352
6-Ethoxybenzo[d]thiazole-2-sulfonamide
BDBM10882
Ethoxzolamide (USP)
NCGC00018249-01
AB00383049_13
Tox21_110848_1
Athamid
3dcw
AI3-50805
SCHEMBL63941
HSDB 3268
Redupresin;L-643786;PNU-4191
NCGC00018249-03
Etoxzolamide
HY-B1480
NCGC00018249-05

MDL Number

MFCD00057089

Customs Code

2935009090

FAQ

What regulatory guidelines apply to 6-Ethoxy-1,3-benzothiazole-2-sulfonamide (CAS: 452-35-7)?

6-Ethoxy-1,3-benzothiazole-2-sulfonamide (CAS: 452-35-7) is subject to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), which requires specific labeling and safety data sheets. In Europe, it must comply with the REACH regulation, which involves registration, evaluation, authorization, and restriction of chemical substances. FDA and EPA regulations also apply for its use in the United States, ensuring that it meets safety and environmental standards.

Are there alternatives to 6-Ethoxy-1,3-benzothiazole-2-sulfonamide in synthesis?

Several alternatives can be used in the synthesis of 6-Ethoxy-1,3-benzothiazole-2-sulfonamide. For example, using different sulfonamides or varying the substituents like ethoxy and other alkyl groups can provide similar functionalities. Analogous benzothiazoles or other heterocycles can also serve as substitutes, depending on the specific requirements of the synthesis.

What is the market or research trend for 6-Ethoxy-1,3-benzothiazole-2-sulfonamide?

The market for 6-Ethoxy-1,3-benzothiazole-2-sulfonamide is growing due to its applications in pharmaceuticals and agrochemicals. Research trends focus on its use as an intermediate in drug discovery and its potential in crop protection. Studies are also exploring its biodegradability and environmental impact to ensure sustainable use.

How should waste containing 6-Ethoxy-1,3-benzothiazole-2-sulfonamide be handled?

Waste containing 6-Ethoxy-1,3-benzothiazole-2-sulfonamide should be collected in appropriate containers and managed according to local regulations. Professional incineration is often recommended for disposal to minimize environmental impact. Precautions include proper ventilation and the use of protective equipment. Always consult the Material Safety Data Sheet (MSDS) for specific handling instructions and local disposal requirements.