2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine | CAS No. 446859-33-2

2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine

Basic Information

CAS Number

446859-33-2

Molecular Formula

C17H13N5

Molecular Weight

287.33 g/mol

AD

Basic Physical Properties

Solubility

DMSO: >20mg/mL

Cc1cccc(n1)c2c(c[nH]n2)c3ccc4c(n3)cccn4

InChI

InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)

InChIKey

LBPKYPYHDKKRFS-UHFFFAOYSA-N

LogP

3.3903200000000018

Topological Polar Surface Area

67.35 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

376

Safety Information

View Safety Information

GHS Hazard Pictograms

H301H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Synonyms & References

English

  • ALK5 INHIBITOR
  • 2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
  • RepSox
  • Alk 5 Inhibitor II
  • 1vjy
  • E616452
  • E-616452
  • GW786460X
  • SJN 2511
  • SJN-2511
  • 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
  • ALK5 Inhibitor II
  • TGF-beta RI Kinase Inhibitor II
  • C17H13N5
  • 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
  • Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor II
  • 2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
  • 2-(5-(6-methylpyridin-2-yl)-1H-pyraz

MDL Number

MFCD09037561

FAQ

What is 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine (CAS: 446859-33-2)?

2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine is a complex heterocyclic compound with a unique structure that includes pyrazole and naphthyridine rings. It exhibits strong biological activity and is primarily used in the development of pharmaceuticals due to its potential as an antiviral agent.

What are the main uses of 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine (CAS: 446859-33-2)?

2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine is mainly used in the pharmaceutical industry as a lead compound for antiviral drugs, particularly against respiratory syncytial virus. It is also studied for its potential in treating other viral infections.

Is 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine (CAS: 446859-33-2) safe?

2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine is generally considered safe for laboratory use under controlled conditions. However, it is important to follow all safety guidelines, including the use of personal protective equipment (PPE) and proper ventilation. Handling should be done with caution due to its potential biological activity.

How should 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine (CAS: 446859-33-2) be stored?

2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Handling should be minimized, and the compound should be stored under conditions that maintain its stability and prevent contamination.

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