N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine | CAS No. 443913-73-3
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
Basic Information
CAS Number
443913-73-3
Molecular Formula
C22H24BrFN4O2
Molecular Weight
475.36 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
234-243°C
Boiling Point
538°C at 760 mmHg
Flash Point
279.3℃
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- NSC-800961
- Caprelsa (TN)
- Tox21_112511_1
- NCGC00167513-01
- 4-[(4-Bromo-2-fluorophenyl)amino]-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazoline
- A25648
- 4-Quninazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-
- D06407
- ZD 6474
- Caprelsa
- EX-A422
- CS-0130
- CHEMBL24828
- 4-BROMO-2-FLUORO-N-((4E)-6-METHOXY-7-((1-METHYLPIPERIDIN-4-YL)METHOXY)QUINAZOLIN-4(1H)-YLIDENE)ANILINE
- cid_3081361
- SW218092-2
- AZD6474
- NSC 744325
- CHEBI:49960
- NCGC00167513-03
- SCHEMBL21067679
- NCGC00167513-04
- CCG-269495
- FT-0656736
- ZD6474
- CH-331
- NCGC00167513-09
- 4-QUINAZOLINAMINE, N-(4-BROMO-2-FLUOROPHENYL)-6-METHOXY-7-((1-METHYL-4- PIPERIDINYL)METHOXY)-
- DTXCID9026681
- ZD6
- SMR002530472
MDL Number
MFCD07772346
Customs Code
2933990090
FAQ
What is N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine (CAS: 443913-73-3)?
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine (CAS: 443913-73-3) is a synthetic organic compound with a complex molecular structure. It contains a quinazoline ring system substituted with bromo, fluoro, methoxy, and a piperidine-derived methoxy group. This compound is known for its potential pharmaceutical applications and is often studied in drug development research.
What are the main uses of N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine (CAS: 443913-73-3)?
The compound is primarily used in pharmaceutical research as a potential inhibitor of certain enzymes, particularly in the development of drugs targeting neurological and inflammatory conditions. It may also be used in chemical synthesis as a building block for more complex molecules. Its applications are still under investigation due to its novel structure and biological activity.
Is N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine (CAS: 443913-73-3) safe?
Safety data for this compound is limited, but it is generally considered to have potential toxicity due to its complex chemical structure. Precautions include wearing appropriate personal protective equipment (PPE) and handling in a well-ventilated area. It should be used in accordance with standard chemical safety protocols and regulatory guidelines to ensure safe handling and minimize exposure risks.
How should N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine (CAS: 443913-73-3) be stored?
This compound should be stored in a cool, dry, and dark place, preferably at 2-8°C. It is sensitive to moisture and light, so it should be kept in a sealed container with desiccant and protected from direct sunlight. Storage conditions should also ensure good ventilation and avoid contact with incompatible materials to maintain stability and safety.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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