Metronidazole | CAS No. 443-48-1

Q: What is Metronidazole (CAS: 443-48-1)?

Metronidazole (CAS: 443-48-1) is an antimicrobial medication used to treat infections caused by anaerobic bacteria and certain protozoa. Its chemical formula is C6H9N3O2, and it belongs to the nitroimidazole class. It is a white to off-white powder, slightly soluble in water, and has a broad spectrum of activity against gram-negative and gram-positive anaerobes. Metronidazole is effective in conditions like bacterial vaginosis, trichomoniasis, and amoebiasis due to its ability to disrupt microbial DNA.

Q: What are the main uses of Metronidazole (CAS: 443-48-1)?

Metronidazole (CAS: 443-48-1) is primarily used in pharmaceuticals to treat infections caused by anaerobic bacteria and protozoa. It is effective against conditions such as periodontal disease, pelvic inflammatory disease, and Giardia lamblia. In industrial settings, it may serve as a preservative. Its antimicrobial properties make it valuable in research for studying bacterial resistance and drug development. Always consult a healthcare professional for specific applications.

Q: Is Metronidazole (CAS: 443-48-1) safe?

Metronidazole (CAS: 443-48-1) is generally safe when used as directed, but it may cause side effects like nausea, headache, or allergic reactions. It is approved by the FDA and WHO for medical use. Proper handling is essential to avoid inhalation or skin contact, especially during manufacturing. Safety standards emphasize adherence to guidelines to minimize risks, and protective measures such as gloves and ventilation should be used during handling.

Q: How should Metronidazole (CAS: 443-48-1) be stored?

Metronidazole (CAS: 443-48-1) should be stored in a cool, dry place away from moisture and light. Maintain temperature below 25°C and keep in a sealed, airtight container. Avoid exposure to humidity and direct sunlight to ensure stability. Proper storage prevents degradation and maintains efficacy. Always store in a secure location to prevent accidental ingestion or contamination.

Metronidazole

Basic Information

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CAS Number

443-48-1

Molecular Formula

C6H9N3O3

Molecular Weight

171.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Powder

Melting Point

159-161 °C

Boiling Point

405.4°C at 760 mmHg

Water Solubility

<0.1 g/100 mL at 20 ºC

Solubility

acetic acid: 0.1 M, clear, faintly yellow

Refractive Index

1.5800 (estimate)

Vapor Pressure

0.0±1.0 mmHg at 25°C

SMILES

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Cc1ncc([N+](=O)[O-])n1CCO

InChI

1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3

InChIKey

VAOCPAMSLUNLGC-UHFFFAOYSA-N

LogP

0.61520

Complexity

170

Safety Information

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GHS Hazard Pictograms

H351

Hazard Statement

H351 Suspected of causing cancer
Carcinogenicity

Storage Conditions

2-8℃

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol
1-(BETA-ETHYLOL)-2-METHYL-5-NITRO-3-AZAPYRROLE
2-(2-METHYL-5-NITRO-1H-IMIDAZOL-1-YL)ETHAN-1-OL
2-(2-methyl-5-nitroimidazol-1-yl)ethanol
2-METHYL-5-NITRO-1-IMIDAZOLEETHANOL
2-METHYL-5-NITRO-1-IMIDAZOLETHANOLE
2-METHYL-5-NITROIMIDAZOLE-1-ETHANOL
AKOS BB-9514
CLONT
flagyl
METRONIDAZOLE
TIMTEC-BB SBB001486
1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole
1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole
1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole
1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole
1H-Imidazole-1-ethanol, 2-methyl-5-nitro-
Metronidazole Benzoate
Metronidazole solution
TB500
2-(2-Methyl-5-nitro-1-imidazolyl)ethanol
Bexon
Cont
Elyzol
Eumin
Flagil
Klion
Klont
Nalox
Nida
[ "" ]

MDL Number

MFCD00009750

Customs Code

2933990090

FAQ

What is Metronidazole (CAS: 443-48-1)?

Metronidazole (CAS: 443-48-1) is an antimicrobial medication used to treat infections caused by anaerobic bacteria and certain protozoa. Its chemical formula is C6H9N3O2, and it belongs to the nitroimidazole class. It is a white to off-white powder, slightly soluble in water, and has a broad spectrum of activity against gram-negative and gram-positive anaerobes. Metronidazole is effective in conditions like bacterial vaginosis, trichomoniasis, and amoebiasis due to its ability to disrupt microbial DNA.

What are the main uses of Metronidazole (CAS: 443-48-1)?

Metronidazole (CAS: 443-48-1) is primarily used in pharmaceuticals to treat infections caused by anaerobic bacteria and protozoa. It is effective against conditions such as periodontal disease, pelvic inflammatory disease, and Giardia lamblia. In industrial settings, it may serve as a preservative. Its antimicrobial properties make it valuable in research for studying bacterial resistance and drug development. Always consult a healthcare professional for specific applications.

Is Metronidazole (CAS: 443-48-1) safe?

Metronidazole (CAS: 443-48-1) is generally safe when used as directed, but it may cause side effects like nausea, headache, or allergic reactions. It is approved by the FDA and WHO for medical use. Proper handling is essential to avoid inhalation or skin contact, especially during manufacturing. Safety standards emphasize adherence to guidelines to minimize risks, and protective measures such as gloves and ventilation should be used during handling.

How should Metronidazole (CAS: 443-48-1) be stored?

Metronidazole (CAS: 443-48-1) should be stored in a cool, dry place away from moisture and light. Maintain temperature below 25°C and keep in a sealed, airtight container. Avoid exposure to humidity and direct sunlight to ensure stability. Proper storage prevents degradation and maintains efficacy. Always store in a secure location to prevent accidental ingestion or contamination.