3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

Basic Information

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CAS Number

442908-10-3

Molecular Formula

C16H15N7O

Molecular Weight

321.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

245.3-246.1 ºC

Boiling Point

668.5±65.0°C at 760 mmHg

SMILES

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Nc1nc(c2ccco2)c2c(n1)n(nn2)Cc1ccc(c(c1)C)N

InChI

InChI=1S/C16H15N7O/c1-9-7-10(4-5-11(9)17)8-23-15-14(21-22-23)13(19-16(18)20-15)12-3-2-6-24-12/h2-7H,8,17H2,1H3,(H2,18,19,20)

InChIKey

HQSBCDPYXDGTCL-UHFFFAOYSA-N

LogP

2.00242

Topological Polar Surface Area

121.67 Å²

Hydrogen Bond Donor/Acceptor

4 / 8

Complexity

439

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-(4-amino-3-methylobenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine
3-[(4-amino-3-methylphenyl)methyl]-7-(furan-2-yl)triazolo[4,5-d]pyrimidin-5-amine
BIIB 014
BIIB-014
Vipadenant （BIIB 014）
Vipadenant(BIIB 014)
3-[(4-Amino-3-methylphenyl)methyl]-7-(2-furanyl)-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine
CEB 4520
V 2006
VER 11135
VER-A 00-11
VER-A 00049
VER-ADO 49
Vipadenant
BIIB014
V2006
LDR3USH1NJ
3-(4-amino-3-methylbenzyl)-7-(furan-2-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine
3-[(4-azanyl-3-methyl-phenyl)methyl]-7-(furan-2-yl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
Vipadenant [USAN:INN]
3-(4-amino-3-methylbenzyl)-7-(2-furyl)-3H-(1,2,3)triazolo(4,5-d)

MDL Number

MFCD12024697

FAQ

What is 3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3)?

3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3) is a complex organic compound with potential applications in pharmaceutical research. It features a triazole ring fused with a pyrimidine ring and a furan substituent.

What are the main uses of 3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3)?

3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3) is primarily used in pharmaceutical research as a potent inhibitor of viral proteases, showing promise in antiviral drug development.

Is 3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3) safe?

3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3) is generally considered safe when handled with appropriate precautions. It is important to follow safety guidelines, including the use of personal protective equipment (PPE) and proper ventilation.

How should 3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3) be stored?

3-(4-Amino-3-methylbenzyl)-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine (CAS: 442908-10-3) should be stored in a tightly sealed container at a temperature not exceeding 25°C, away from direct sunlight and sources of heat. Maintain the storage area dry and well-ventilated.