Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone | CAS No. 442847-66-7

Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone

Basic Information

CAS Number

442847-66-7

Molecular Formula

C23H31ClN4O7S

Molecular Weight

543 g/mol

AD

Basic Physical Properties

Melting Point

133-138°C

CC(C1C2CC(=C(N2C1=O)C(=O)OCC3=CC=C(C=C3)[N+](=O)[O-])SCCN)O.CN1CCCC1=O.Cl

InChI

InChI=1S/C18H21N3O6S.C5H9NO.ClH/c1-10(22)15-13-8-14(28-7-6-19)16(20(13)17(15)23)18(24)27-9-11-2-4-12(5-3-11)21(25)26;1-6-4-2-3-5(6)7;/h2-5,10,13,15,22H,6-9,19H2,1H3;2-4H2,1H3;1H/t10-,13-,15-;;/m1../s1

InChIKey

RISUKBNXUNVOJK-OSSMXLPMSA-N

LogP

0.25250

Complexity

761

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 4-Nitrobenzyl (5R,6S)-3-((2-aminoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate--1-methylpyrrolidin-2-one
  • 442847-66-7
  • AKOS025402088
  • AC-4679
  • Thienamycin p-nitrobenzylester hydrochloride
  • 1-methylpyrrolidin-2-one;(4-nitrophenyl)methyl (5R,6S)-3-(2-aminoethylsulfanyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate;hydrochloride
  • THIENAMYCIN P-NITROBENZYLESTER, N-METHYLPYRROLIDINONE HCL
  • Thienamycin p-nitrobenzyl ester, N-methylpyrrolidinone HCl
  • Thienamycin p-nitrobenzylester hydrochloride (N-methylpyrrolidinonesolvate)
  • (4-nitrophenyl)methyl (5R,6S)-3-[(2-aminoethyl)sulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 1-methylpyrrolidin-2-one hydrochloride
  • 3-[(2-Aminoethyl)thio]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methylester monohydrochloride compd. with 1-methyl-2-pyrrolidinone (1:1)
  • 4) THIENAMYCIN P-NITROBENZYLESTER HYDROCHLORIDE (N-METHYLPYRROLIDINONESOLVATE)
  • p-Nitrobenzyl (5R,6S)-2-(diphenylphosphoryloxy)-6-((1R)-1-hydroxyethyl)carbapen-2-em-3-carboxylate
  • IMIPENEM INTERMEDIATE
  • INTERMEDIATE OF IMIPENEM
  • p-Nitrobenzyl (5R,6S)-2-(diphenylphos
  • PROTECTED THIENCIN HYDROCHLORIDE
  • THIENAMYCIN P-NITROBENZYL ESTER HYDROCHLORIDE
  • THIENAMYCIN P-NITROBENZYLESTER HCL(N-METHYLPYRROLIDINONESOLVATE)
  • ThienaMycin p-nitrobenzylester,N-Methylpyrrolidinone HCl

MDL Number

MFCD08458462

FAQ

What regulatory guidelines apply to Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7)?

Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7) requires adherence to regulatory guidelines such as the GHS for hazardous classification, REACH for EU regulations, and FDA/EPA requirements for safety and environmental standards. Specific regulations include material safety data sheets (MSDS), toxicology assessments, and compliance with safe handling practices.

Are there alternatives to Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7) in synthesis?

Alternatives to Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7) in synthesis include using different esterifying reagents or modifying the chemical structure. Common alternatives include using different p-nitrobenzyl esters or substituting N-methylpyrrolidinone with other solvents like dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).

What is the market or research trend for Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7)?

The market trend for Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7) is growing with increasing research interest in its potential applications in pharmaceuticals and biotechnology. Emerging trends include exploring its use as a precursors in drug synthesis and studying its biological activity. However, market dynamics are influenced by cost and availability of raw materials.

How should waste containing Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7) be handled?

Waste containing Thienamycin p-Nitrobenzyl Ester with N-Methylpyrrolidinone (CAS: 442847-66-7) should be collected in sealed containers and disposed of through professional waste disposal services. Incineration is a common method for disposal, and environmental precautions include ensuring no hazardous emissions. Proper documentation and compliance with local regulations are essential for safe waste handling.

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