4-Bromo-3-methoxybenzaldehyde

Basic Information

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CAS Number

43192-34-3

Molecular Formula

C8H7BrO2

Molecular Weight

215.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

126-127 ºC (dichloromethane )

Boiling Point

289.7±25.0 ºC (760 Torr),

Flash Point

129.0±23.2 ºC,

SMILES

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COc1cc(C=O)ccc1Br

InChI

InChI=1S/C8H7BrO2/c1-11-8-4-6(5-10)2-3-7(8)9/h2-5H,1H3

InChIKey

HKLCOMKRVBQSHA-UHFFFAOYSA-N

LogP

2.2702

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-Bromo-3-methoxybenzaldehyde
3-methoxy-4-bromobenzaldehyde
4-Br-3-MeOC6H3CHO
4-Brom-3-methoxy-benzaldehyd
4-bromo-3-methoxy-benzaldehyde
ACMC-209jtf
AM80895
ANW-29953
Benzaldehyde, 4-bromo-3-methoxy-
CL4557
CTK1C8153
4-bromo-3-methoxybenzaldehyde

MDL Number

MFCD11846303

FAQ

What are the physical and chemical properties of 4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3)?

4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3) is a crystalline solid with a molecular weight of approximately 244.05 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution reactions. It is also prone to oxidation reactions.

How is 4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3) typically synthesized?

4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3) is commonly synthesized via bromination of 3-methoxybenzaldehyde using N-bromosuccinimide (NBS) as the brominating agent in the presence of a suitable oxidant like benzoyl peroxide. The reaction yields a high percentage of the desired product with good selectivity.

What industries use 4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3)?

4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3) finds applications in the pharmaceutical industry for the synthesis of certain intermediates and drugs. It is also used in the production of polymers and as a precursor in sensor and semiconductor manufacturing due to its chemical reactivity and functional groups.

What precautions should be taken when handling 4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3)?

When handling 4-Bromo-3-methoxybenzaldehyde (CAS: 43192-34-3), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a fume hood to avoid inhalation. In case of a spill, neutralize with a suitable reagent and dispose of according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.