Alogliptin Impurity 24

Basic Information

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CAS Number

4318-56-3

Molecular Formula

C5H5ClN2O2

Molecular Weight

160.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

278°C

Boiling Point

225.3°C at 760 mmHg

Flash Point

268.7 °Cat760mmHg

Refractive Index

1.58

SMILES

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Cn1c(=O)cc(Cl)[nH]c1=O

InChI

InChI=1S/C5H5ClN2O2/c1-8-4(9)2-3(6)7-5(8)10/h2H,1H3,(H,7,10)

InChIKey

SGLXGFAZAARYJY-UHFFFAOYSA-N

LogP

-0.2730000000000002

Topological Polar Surface Area

54.86 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

224

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-Methyl-6-chlorouracil
6-chloro-3-methyl-2,4(1H,3H)-pyrimidinedione
6-chloro-3-methylpyrimidine-2,4(1H,3H)-dione
6-Chloro-3-dimethyl uracil
3-METHYL-6-CHLOROURACI
6-Chloro-3-Methyuracil
6-Chloro-3-methyluracil
6-chloro-3-methyl-1H-pyrimidine-2,4-dione
6-Chloro-3-methyl-uracil
6-chlorouracil-3-Methyl
CinnaMaMide, PredoMinantly trans
2,4(1H,3H)-Pyrimidinedione, 6-chloro-3-methyl-
6-CHLORO-2-HYDROXY-3-METHYL-3,4-DIHYDROPYRIMIDIN-4-ONE
6-chloro-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
6-Chloro-3-methylpyrimidine-2,4[1H,3H]-dione
NSC55976
zlchem 383
PubChem4065
6-Chloro-3-methyl uracil
MLS00

MDL Number

MFCD01074837

Customs Code

2933599090

FAQ

What is Alogliptin Impurity 24 (CAS: 4318-56-3)?

Alogliptin Impurity 24 (CAS: 4318-56-3) is a specific byproduct or contaminant associated with the synthesis of alogliptin, a DPP-4 inhibitor used in diabetes treatment. It is a pharmaceutical impurity with a molecular structure related to the parent compound, often requiring analysis to ensure drug purity and safety. Its exact chemical formula and physical properties depend on the synthesis pathway, but it is typically characterized by its presence in trace amounts during quality control testing.

What are the main uses of Alogliptin Impurity 24 (CAS: 4318-56-3)?

Alogliptin Impurity 24 (CAS: 4318-56-3) is primarily used in pharmaceutical research for the identification and analysis of impurities in drug manufacturing processes. It plays a critical role in ensuring the purity of alogliptin, a medication for type 2 diabetes, and is also relevant in drug development for compliance with regulatory standards. Its presence is monitored to assess potential safety risks and optimize synthetic methods.

Is Alogliptin Impurity 24 (CAS: 4318-56-3) safe?

Alogliptin Impurity 24 (CAS: 4318-56-3) is not intended for therapeutic use and is generally considered safe in controlled environments when handled properly. However, as a chemical impurity, it may pose risks if exposed in high concentrations. Safety precautions include wearing protective gear and following standard laboratory protocols. Its toxicity profile is typically low, but specific safety data should be referenced based on its chemical structure and impurity classification.

How should Alogliptin Impurity 24 (CAS: 4318-56-3) be stored?

Alogliptin Impurity 24 (CAS: 4318-56-3) should be stored in a cool, dry place, away from direct light, in airtight containers to maintain stability. It is typically kept at 2-8°C to prevent degradation, and humidity levels should be controlled to avoid moisture-related reactions. Proper storage ensures its integrity for analytical testing and adherence to pharmaceutical quality standards.