5-Amino-1-benzofuran-2-carboxylic acid

Basic Information

View in Editor

CAS Number

42933-44-8

Molecular Formula

C9H7NO3

Molecular Weight

177.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

>300°

SMILES

View in Editor

C1=CC2=C(C=C1N)C=C(O2)C(=O)O

InChI

InChI=1S/C9H7NO3/c10-6-1-2-7-5(3-6)4-8(13-7)9(11)12/h1-4H,10H2,(H,11,12)

InChIKey

IIBKBXGCIDLMOP-UHFFFAOYSA-N

LogP

1.7132

Topological Polar Surface Area

76.46 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

219

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

DTXSID60624044
2-Benzofurancarboxylicacid, 5-amino-
5-amino-1-benzofuran-2-carboxylic acid
AC-26399
SCHEMBL3487776
BCP01669
AMY21354
AKOS005072745
MFCD11505019
5-Aminobenzofuran-2-carboxylicacid
J-516732
2-Benzofurancarboxylic acid,5-amino-
A851629
5-aminobenzofuran-2-carboxylic acid
FT-0681069
AB01002291-01
2-Benzofurancarboxylic acid, 5-amino-
42933-44-8
GC-0616
CS-M1933
EN300-41999
5-Aminobenzofuran-2-carboxylic acid
5-amino-1-benzofuran-2-carboxylic acid
2-Benzofurancarboxylic acid,5-amino
5-Amino-benzofuran-2-carbonsaeure
5-amino-benzofuran-2-carboxylic acid
aminobenzofurancarboxylicacid

MDL Number

MFCD11505019

Customs Code

2932999099

FAQ

What regulatory guidelines apply to 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8)?

5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8) is subject to various regulatory guidelines. It falls under the Control of Substances Hazardous to Health (COSHH) in the UK and is classified under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous substance. In the EU, it is governed by REACH regulations, which require registration, evaluation, and authorization for certain uses. Additionally, the FDA and EPA have specific requirements for the import, storage, and handling of this compound in the USA.

Are there alternatives to 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8) in synthesis?

Yes, there are alternatives to 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8) in synthesis. Commonly used alternatives include other aromatic carboxylic acids, such as benzoic acid or hydroxybenzoic acid, and their derivatives. Isomers like 2-Amino-1-benzofuran-5-carboxylic acid can also be considered. For specific applications, researchers often explore synthetic analogs that match the desired properties but may have better safety or reactivity profiles.

What is the market or research trend for 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8)?

The market and research trends for 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8) are driven by its use in pharmaceuticals, especially in the development of antiviral and anticancer drugs. Recent research focuses on its potential as a precursor in medicinal chemistry and as a scaffold for drug discovery. Market trends indicate increasing demand due to its unique chemical properties, although price fluctuations can impact availability. The compound's promising therapeutic potential continues to attract significant research interest.

How should waste containing 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8) be handled?

Waste containing 5-Amino-1-benzofuran-2-carboxylic acid (CAS: 42933-44-8) should be handled with care to ensure environmental safety. Waste liquids should be collected in appropriate containers and disposed of through professional waste disposal services. Incineration is a common method for disposal, but it must be conducted in an environmentally safe manner. Precautions include proper labeling, avoiding exposure to air and moisture, and adherence to local regulations regarding hazardous waste management. Always consult the Material Safety Data Sheet (MSDS) and follow local guidelines for safe disposal.